BackgroundPalonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though
Belen Sadaba +10 more
doaj +1 more source
Comparison of palonosetron with ondansetron in prevention of postoperative nausea and vomiting in patients receiving intravenous patient-controlled analgesia after gynecological laparoscopic surgery [PDF]
BackgroundPostoperative nausea and vomiting (PONV) are common complications after anesthesia and surgery. This study was designed to compare the effects of palonosetron and ondansetron in preventing PONV in high-risk patients receiving intravenous opioid-
Yu Yil Kim +5 more
doaj +1 more source
Consensus recommendations for the prevention of vomiting and nausea following high-emetic-risk chemotherapy [PDF]
In this update of our 2005 document, we used an evidence-based approach whenever possible to formulate recommendations, emphasizing the results of controlled trials concerning the best use of antiemetic agents for the prevention of emesis and nausea ...
Ballatori, Enzo +11 more
core +1 more source
Background and Aims: Postanesthesia shivering (PAS) is a common, distressing experience. Ondansetron, the classical 5HT3 antagonist has been in use for its prevention since long.
Manoj K Sharma +2 more
doaj +1 more source
Acute emesis: moderately emetogenic chemotherapy [PDF]
This paper is a review of the recommendations for the prophylaxis of acute emesis induced by moderately emetogenic chemotherapy as concluded at the third Perugia Consensus Conference, which took place in June 2009.
Bria, Emilio +6 more
core +1 more source
Randomised Control Study of Palonosetron Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting Following Ear and Nose Surgeries under General Anesthesia [PDF]
Introduction: Postoperative Nausea and Vomiting (PONV) is defined as any nausea or vomiting that occurs during the first 48 hours after surgery. It is considered as a distressing event following anaesthesia.
Anju Annie Paul +6 more
doaj +1 more source
Wie zum Beispiel Ondansetron wirkt Palonosetron gegen Brechreiz und Erbrechen im Zusammenhang mit emetogener Chemotherapie.
openaire +1 more source
Phase II study of fosaprepitant + 5HT3 receptor antagonist + dexamethasone in patients with germ cell tumors undergoing 5-day cisplatin-based chemotherapy: A Hoosier Cancer Research Network Study [PDF]
Purpose A phase III study adding aprepitant to a 5HT3 receptor antagonist (5HT3-RA) plus dexamethasone in germ cell tumor (GCT) patients treated with 5-day cisplatin combination chemotherapy demonstrated a significant improvement in complete response (
Adra, Nabil +11 more
core +2 more sources
Background and Aims: Post-operative nausea and vomiting (PONV) is highly distressing and unpleasant symptom. Dexamethasone and palonosetron are effective antiemetics with minimal side effect profile.
Arindam Chatterjee +5 more
doaj +1 more source
Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting [PDF]
BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy.
Bajaj, Madhuri +9 more
core +1 more source

