Results 11 to 20 of about 2,968 (201)

Randomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapy. [PDF]

open access: yesPLoS ONE, 2014
BackgroundPalonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though
Belen Sadaba   +10 more
doaj   +3 more sources

A Case of Possible Infusion-Related Reactions Caused by Palonosetron

open access: yesCase Reports in Oncology
Introduction: An infusion-related reaction (IRR) is an adverse event that typically occurs when cytotoxic drugs or monoclonal antibodies are administered.
Toru Kadono   +4 more
doaj   +2 more sources

Comparison of efficacy of palonosetron-dexamethasone combination with palonosetron or dexamethasone alone for prophylaxis against post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

open access: yesIndian Journal of Anaesthesia, 2017
Background and Aims: Post-operative nausea and vomiting (PONV) is highly distressing and unpleasant symptom. Dexamethasone and palonosetron are effective antiemetics with minimal side effect profile.
Arindam Chatterjee   +5 more
doaj   +2 more sources

Palonosetron for the prevention of chemotherapy-induced nausea and vomiting: approval and efficacy

open access: yesCancer Management and Research, 2009
Rudolph M NavariIndiana University School of Medicine South Bend, South Bend, IN USAAbstract: Chemotherapy-induced nausea and vomiting (CINV) is associated with a significant deterioration in quality of life.
Rudolph M Navari
doaj   +3 more sources

Effects of palonosetron and ondansetron on preventing nausea and vomiting after laparoscopic surgery

open access: yesJournal of International Medical Research, 2018
Background This meta-analysis was performed to evaluate the efficacy and safety of palonosetron and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic surgery with general anesthesia.
Qili Liu   +3 more
doaj   +2 more sources

Palonosetron and Ramosetron Compared for Effectiveness in Preventing Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis.

open access: yesPLoS ONE, 2016
Previous randomized controlled trials have reported conflicting findings on the superiority of palonosetron over ramosetron for preventing postoperative nausea and vomiting (PONV).
EunJin Ahn   +7 more
doaj   +2 more sources

Higher dose of palonosetron versus lower dose of palonosetron plus droperidol to prevent postoperative nausea and vomiting after eye enucleation and orbital hydroxyapatite implant surgery: a randomized, double-blind trial

open access: yesDrug Design, Development and Therapy, 2017
Xiao Hu, Fang Tan, Lan Gong Department of Anesthesiology, The Eye, Ear, Nose and Throat Hospital of Fudan University, Shanghai Medical College of Fudan University, Shanghai, China Objective: Postoperative nausea and vomiting (PONV) is ...
Hu X, Tan F, Gong L
doaj   +1 more source

Update on the management of chemotherapy-induced nausea and vomiting – focus on palonosetron

open access: yesTherapeutics and Clinical Risk Management, 2015
Michelle Zhou, Marko Popovic, Mark Pasetka, Natalie Pulenzas, Soha Ahrari, Edward Chow, Carlo DeAngelis Department of Pharmacy, Odette Cancer Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada Purpose: Nausea and
Zhou M   +6 more
doaj   +1 more source

Comparative evaluation of ondansetron, palonosetron, and dexamethasone for antiemetic prophylaxis in cesarean section under spinal anaesthesia

open access: yesAsian Journal of Medical Sciences
Background: Spinal anesthesia is the most common regional anesthesia used to provide surgical anesthesia for cesarean section. Nausea and vomiting are common symptoms experienced by patients undergoing cesarean section. Aims and Objectives: The aim of
Vankudoth Bhaskar   +3 more
doaj   +2 more sources

A comparative study between palonosetron and granisetron to prevent postoperative nausea and vomiting after laparoscopic cholecystectomy

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2010
Background: Postoperative nausea and vomiting (PONV) is commonly seen after laparoscopic surgery. In this randomized double blind prospective clinical study, we investigated and compared the efficacy of palonosetron and granisetron to prevent ...
Dhurjoti Prosad Bhattacharjee   +5 more
doaj   +1 more source

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