Results 31 to 40 of about 4,295 (215)

Antiemetic research: future directions [PDF]

, 2010
PURPOSE AND METHODS: As a part of reviewing the Multinational Association of Supportive Care in Cancer (MASCC) antiemetic guidelines in Perugia in 2009, an expert group identified directions for future antiemetic research.
Aapro, Matti, Grunberg, Steven, Herrstedt, Jørn, Molassiotis, Alexander, Morrow, Garry, Olver, Ian   +5 more
core   +1 more source

Palonosetron-5-HT3Receptor Interactions As Shown by a Binding Protein Cocrystal Structure. [PDF]

, 2016
Palonosetron is a potent 5-HT3receptor antagonist and an effective therapeutic agent against emesis. Here we identify the molecular determinants of compound recognition in the receptor binding site by obtaining a high resolution structure of palonosetron
Lillestol, Reidun K, Lummis, Sarah CR, Price, Kerry L, Ulens, Chris   +3 more
core   +1 more source

Palonosetron has superior prophylactic antiemetic efficacy compared with ondansetron or ramosetron in high-risk patients undergoing laparoscopic surgery: a prospective, randomized, double-blinded study [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundPostoperative nausea and vomiting (PONV) continues to be a major problem, because PONV is associated with delayed recovery and prolonged hospital stay.
Sung-Hoon Kim, Jeong-Yeon Hong, Won Oak Kim, Hae Keum Kil, Myong-Hwan Karm, Jai-Hyun Hwang   +5 more
doaj   +1 more source

NEPA, a new fixed combination of netupitant and palonosetron, is a cost-effective intervention for the prevention of chemotherapy-induced nausea and vomiting in the UK [PDF]

, 2017
Background: The objective was to evaluate the cost-effectiveness of NEPA, an oral fixed combination netupitant (NETU, 300 mg) and palonosetron (PA, 0.5 mg) compared with aprepitant and palonosetron (APPA) or palonosetron (PA) alone, to prevent ...
Bourhis, Francois, Cawston, Helene, Di'Agostino, Paolo, Eriksson, Jennifer, McGuire, Alistair, Ruffo, Pierfrancesco, Schwartzberg, Lee, Turini, Marco   +7 more
core   +3 more sources

Reasons for delayed patient discharge following day surgery: a literature review [PDF]

, 2016
NHS Trusts face considerable financial challenges. There is a drive to reduce costs by increasing day surgery rates, thereby reducing the length of post-operative stay.
Alison Rae, Rae, Alison
core   +1 more source

A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. [PDF]

, 2018
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Aapro, Aapro, Aapro, Ahmad, Alphin, Amin, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Angeli, Anttila, Appl, Armstrong, Ash, Atkinson, Axelsson, Babaoglu, Babkin, Baker, Bakker, Balaban, Barone, Batchelor, Benchaoui, Benchaoui, Bergeron, Bermudez, Bertaccini, Bertolini, Bhandari, Bhargava, Bianchi, Bignall, Birtley, Blair, Bockaert, Boisson, Booth, Borison, Borison, Borison, Borsook, Bountra, Boyd, Boyd, Boyle, Bradley, Brand, Brand, Briejer, Broad, Broad, Broad, Brogden, Brown, Bury, Bymaster, Camilleri, Camilleri, Carlsson, Carpenter, Carpenter, Cassidy, Cavella, Chakrabarti, Champion, Chandrasekharan, Chin, Chiu, Christie, Chu, Church, Clark, Clarke, Claude, Cooper, Coskun, Costall, Courvoisier, Crampton, Creytens, Currow, Danjoux, Darmani, Davis, de la Puente-Redondo, Diemunsch, Dietz, Dionne, Donovan, Douglas, Dumuis, Eglen, Emanuel, Ennis, Erspamer, Erspamer, Fairweather, Fangmann, Farmer, Faustini, Flaxman, Floczyk, Foubert, Fozard, Fozard, Fozard, Friend, Friend, Gaddum, Gardner, Gay, Gesztesi, Gibbs, Glaviano, Goddard, Golding, Golding, Gralla, Gralla, Greaves, Guttuso, Guttuso, Gylys, Gylys, Hale, Hamik, Harrington, Harris, Hasler, Hatcher, Hatcher, Hawthorn, Heckert, Helke, Henry, Herrstedt, Hesketh, Hill, Hill, Hocking, Holbrook, Holling, Holling, Holmes, Horn, Horn, Horn, Hornby, Hromatka, Huang, Huppert, Irwin, Isaacs, Ison, Jacoby, Janssen, Javid, Johnston, Jones, Jordan, Justin-Besancon, Justin-Besancon, Kail, Kanba, Keating, Kebabian, Keiser, Kennis, Kenward, Kim, King, Kirchner, Koch, Koch, Kojima, Kramer, Kranke, Kris, Kroeze, Kubo, Kundu, Lackner, Laird, Lal, Lang, Lau, Lau, Lee, Lees-Green, Leggio, Lembo, Lembo, Lentz, Lewis, Limebeer, Liu, Lu, Lu, Lundberg, López-Muñoz, Maceira, MacIntosh, Maggi, Markey, Marrinan, McEachern, McFarlane, McLean, McRitchie, Meek, Meltzer, Midani, Millan, Miller, Minami, Miner, Miner, Miner, Minton, Moertel, Money, Moreland, Moyer, Muchatuta, Napadow, Navari, Navari, Newton, Ng, Noble, Norton, O'Grady, Oman, Ortiz, Owens, Owyang, Palazzo, Parker, Parkinson, Pasricha, Peeters, Penta, Percie du Sert, Percie du Sert, Peroutka, Peroutka, Pickel, Pinder, Plezia, Prakash, Profet, Profet, Reason, Reason, Reavley, Reinhardt, Rennie, Revicki, Rhee, Rich, Ritter, Robinson, Rock, Rojas, Rojas, Rojas, Rosenfeld, Rupniak, Sallen, Saller, Sam, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Saria, Sawhney, Schmidt, Schulze-Delrieu, Schurig, Sclocco, Sigwald, Simoneau, Simons, Sirven, Slater, Smith, Smith, Sneader, Snider, Snyder, Soergel, Soto, Soukop, Spinks, Srivastava, Stadler, Stefanini, Stern, Stern, Stoltz, Sugino, Takatani, Tattersall, Tattersall, Thearle, Tonato, Tremblay, Tsuji, Tu, Ueno, Ueno, Vail, Van Sickle, Vincent, von Euler, von Euler, Wampler, Wang, Wang, Wang, Warr, Warr, Watson, Watson, Weerts, Weigel, Whitwam, Wong, Wyant, Yates, Zhong   +349 more
core   +3 more sources

Palonosetron versus ondansetron for prevention of nausea and vomiting after total abdominal hysterectomy under spinal anesthesia with intrathecal morphine: a double-blind, randomized controlled trial

BMC Anesthesiology, 2019
Background Hysterectomy is a widely performed surgery and neuraxial anesthesia with intrathecal morphine provides superior quality of recovery. Postoperative nausea and vomiting (PONV) is a frequent problem with intrathecal morphine use.
Guilherme Oliveira Campos, Marcelo de Jesus Martins, Gabriel Nascimento Jesus, Paulo Roberto Rios de Oliveira, Caio Nogueira Lessa, João Carlos Macêdo Fernandes de Oliveira Junior, Lucas Jorge Santana de Castro Alves, Rodrigo Leal Alves, Norma Sueli Pinheiro Módolo   +8 more
doaj   +1 more source

Palonosetron and Ramosetron Compared for Effectiveness in Preventing Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis.

PLoS ONE, 2016
Previous randomized controlled trials have reported conflicting findings on the superiority of palonosetron over ramosetron for preventing postoperative nausea and vomiting (PONV).
EunJin Ahn, GeunJoo Choi, Hyun Kang, ChongWha Baek, YongHun Jung, YoungCheol Woo, SangSeok Lee, YeoGoo Chang   +7 more
doaj   +1 more source

A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries

Journal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: Postoperative nausea and vomiting (PONV) has multifactorial etiology. It is a commonly encountered morbidity after anesthesia specially following middle ear surgery. Various antiemetic medications have been tried with mixed responses.
Shubhangi Sharma, Sangeeta Khanna, Jyotirmoy Das, Yatin Mehta, Kumud Kumar Handa   +4 more
doaj   +1 more source

A randomized, double-blind study to evaluate the efficacy of ramosetron and palonosetron for prevention of postoperative nausea and vomiting after gynecological laparoscopic surgery [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundPostoperative nausea and vomiting (PONV) is a common complication after anesthesia and surgery; 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists have been considered as a first-line therapy.
Soo Kyoung Park, Eun Jung Cho, Sung Hee Kang, Young Jun Lee, Dal-Ah Kim   +4 more
doaj   +1 more source