Results 51 to 60 of about 4,295 (215)

A randomized phase II trial of gemcitabine, nab‐paclitaxel, cisplatin with or without a medically supervised ketogenic diet for patients with metastatic pancreatic cancer

Cancer, Volume 132, Issue 6, 15 March 2026.
ABSTRACT Background A randomized phase II screening trial of gemcitabine, nab‐paclitaxel, and cisplatin with a medically supervised ketogenic diet (MSKD) versus usual diet (non‐MSKD) was conducted in patients with treatment‐naive metastatic pancreatic ductal adenocarcinoma (PDAC).
Gayle S. Jameson, Denise J. Roe, Erkut Borazanci, Diana L. Hanna, Caroline G. P. Roberts, Meredith S. Pelster, Richard C. Frank, Angela T. Alistar, Alan M. Miller, J. Erin Wiedmeier‐Nutor, Sandra D. Algaze, Alison R. Zoller, Sarah J. Hallberg, Betsy C. Wertheim, Keehoon Lee, Derek Cridebring, Joshua D. Rabinowitz, Stephen Gately, Jennifer Keppler, Sunil Sharma, Daniel D. Von Hoff, Drew W. Rasco   +21 more
wiley   +1 more source

Case Report of Acute Severe Hyponatremia Induced by Desmopressin Administration During Chemotherapy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Patients undergoing chemotherapy are prone to developing hyponatremia due to insufficient oral intake because of nausea and vomiting, administration of large volumes of intravenous fluids, syndrome of inappropriate antidiuretic hormone secretion induced by chemotherapeutic agents, adrenal insufficiency, and drug interactions.
Koutaro Ono, Shugo Uematsu, Aya Yoshihara, Ayako Tsuboya, Shoichi Mori, Takashi Yoshioka, Shuichi Nawata   +6 more
wiley   +1 more source

Transversus abdominis plane block reduces remifentanil and propofol consumption, evaluated by closed-loop titration guided by bispectral index. [PDF]

, 2018
The present prospective, randomized, double-blind study aimed to determine the impact of transversus abdominis plane (TAP) block on propofol and remifentanil consumption, when administered by closed-loop titration guided by processed ...
Jiang, Mei-Ru, Li, Tao, Liu, Gang-Gang, Liu, Hong, Ma, Jiahai, Sun, Qiao-Xia, Wang, Xue-Yan, Zhou, Jon   +7 more
core  

Electroacupuncture for Managing Chemotherapy‐Induced Gastrointestinal Symptom Clusters in Patients With Breast Cancer: Study Protocol for a Randomized Controlled Trial

Health Care Science, Volume 5, Issue 1, Page 85-94, February 2026.
This multicenter randomized controlled trial evaluates electroacupuncture combined with standard antiemetics for managing chemotherapy‐induced gastrointestinal symptom clusters in patients with breast cancer. Integrated multi‐omics analyses aim to explore underlying mechanisms, offering potential non‐pharmacological strategies to enhance symptom ...
Xinlong Tao, Zhen Liu, Miaozhou Wang, Dengfeng Ren, Fuxing Zhao, Hongbin Wang, Guowang Yang, Ganlin Zhang, Zitao Li, Zhilin Liu, Shifen Huang, Yongzhi Chen, Mengting Da, Xiaoyan Ma, Hongxia Liang, Yongxin Li, Yinyin Ye, Yonghui Zheng, Xiao Liang, Guoshuang Shen, Xiaorong Bai, Jiuda Zhao   +21 more
wiley   +1 more source

A National Audit of Current UK Practice on the Use of Anti‐Emetics for Chemotherapy‐Induced Nausea and Vomiting in Children

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT This UK national audit aimed to assess adherence to evidence‐based chemotherapy‐induced nausea and vomiting (CINV) guidelines for children with cancer, which emphasise treatment emetogenicity assessment, symptom monitoring and appropriate antiemetic use.
Eloise Neumann, Thomas J. Jackson, Jessica E. Morgan, Robert Phillips, Jessica Bate, the CCLG Supportive Care Group   +5 more
wiley   +1 more source

Feasibility of Using Deep Learning to Detect Hypoxemia During Painless Gastrointestinal Endoscopy Based on Facial Images

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
Objective To develop and validate deep learning (DL) and machine learning (ML) models based on preoperative facial images and structured clinical data for predicting hypoxemia during adult painless gastrointestinal endoscopy, addressing the limitations of subjective and data‐intensive prediction methods. Methods A total of 424 patients aged 18–80 years
Zhihu Yang, Fei Xing, Zhongyu Wang, Mingcui Qu, Yongchao Yao, Yafei Liu, Mingzhu Jing, Mingquan Xing, Jiaqi Chen, Dan Cheng, Na Xing, Ronald G. Pearl   +11 more
wiley   +1 more source

Eficacia y seguridad del Palonosetron en comparacion con Ondansetron en el tratamiento de la Nausea y el Vomito inducido por Quimioterapia en Ninos con Cancer en el Hospital Materno Infantil, ISSEMYM [PDF]

, 2013
EFICACIA Y SEGURIDAD DEL PALONOSETRON EN COMPARACION CON ONDANSETRON EN EL TRATAMIENTO DE LA NAUSEA Y EL VOMITO INDUCIDO POR QUIMIOTERAPIA EN NIÑOS CON CANCER, TRATADOS EN EL HOSPITAL MATERNO INFANTIL ...
Gómez Medina, Mónica Patricia, López Facundo, Norma Araceli   +1 more
core  

Cost Effectiveness of First-Line Treatment with Doxorubicin/Ifosfamide Compared to Trabectedin Monotherapy in the Management of Advanced Soft Tissue Sarcoma in Italy, Spain, and Sweden [PDF]

, 2013
BACKGROUND: Doxorubicin/ifosfamide is a first-line systemic chemotherapy for the majority of advanced soft tissue sarcoma (ASTS) subtypes. Trabectedin is indicated for the treatment of ASTS after failure of anthracyclines and/or ifosfamide; however it is
Gough, N, Guest, JF, Linch, M, Panca, M, Sladkevicius, E   +4 more
core   +2 more sources

Management of Propofol Infusion Pain: An Easy Task for Anesthetists

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
The aim of the present study is to lay out what the literature emphasizes regarding this topic, specifically the use of several drugs and their various doses, while explaining the mechanism of each agent, as well as discussing the comparison between lidocaine and these drugs, so that subsequent trials and investigators could rely on it when planning ...
Mohammed I. A. Ismail, Lou’i Al-Husinat, Omar Mar’ey, Ajwad Obeidat, Ahmad Bakkar, Qutaiba Manasrah, Ismail M. I. Ismail, Srijoni Sengupta   +7 more
wiley   +1 more source

A double‐blind, randomized, multicenter phase 3 study of palonosetron vs granisetron combined with dexamethasone and fosaprepitant to prevent chemotherapy‐induced nausea and vomiting in patients with breast cancer receiving anthracycline and cyclophosphamide

Cancer Medicine, 2020
Purpose To investigate whether palonosetron is better than granisetron in preventing chemotherapy‐induced nausea and vomiting (CINV) in a three‐drug combination with dexamethasone and fosaprepitant (Fos) in patients with breast cancer who are placed on ...
Koji Matsumoto, Masato Takahashi, Kazuhiko Sato, Akihiko Osaki, Toshimi Takano, Yoichi Naito, Kazuo Matsuura, Kenjiro Aogi, Kimiko Fujiwara, Kenji Tamura, Motoi Baba, Shinya Tokunaga, Gen Hirano, Shigeru Imoto, Chieko Miyazaki, Kazuhiro Yanagihara, Chiyo K. Imamura, Yasutaka Chiba, Toshiaki Saeki   +18 more
doaj   +1 more source