Results 71 to 80 of about 4,295 (215)

Intravenous palonosetron increases the incidence of QTc prolongation during sevoflurane general anesthesia for laparotomy [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundPalonosetron is a recently introduced 5-hydroxytryptamine-3 (5-HT3) receptor antagonist useful for postoperative nausea and vomiting prophylaxis.
Jeong Jin Min, Yongjae Yoo, Tae Kyong Kim, Jung-Man Lee   +3 more
doaj   +1 more source

Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: integrated analysis of data from Study 10 and ARIEL2 [PDF]

, 2017
Objective: An integrated analysis was undertaken to characterize the antitumor activity and safety profile of the oral poly(ADP-ribose) polymerase inhibitor rucaparib in patients with relapsed high-grade ovarian carcinoma (HGOC). Methods: Eligible
Bell-McGuinn, Katherine, Brenton, James D., Castro, Cesar M., Chen, Lee-may, Coleman, Robert L., Giordano, Heidi, Goble, Sandra, Konecny, Gottfried E., Kristeleit, Rebecca S., Leary, Alexandra, Lin, Kevin K., Ma, Ling, Maloney, Lara, Mcneish, Iain A., Oaknin, Ana, Oza, Amit M., O’Malley, David M., Provencher, Diane, Raponi, Mitch, Ray-Coquard, Isabelle, Rolfe, Lindsey, Shapira-Frommer, Ronnie, Sun, James, Swisher, Elizabeth M., Tinker, Anna V.   +24 more
core   +1 more source

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

MedComm, Volume 6, Issue 9, September 2025.
This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily
Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu   +7 more
wiley   +1 more source

Effects of pretreatment with intravenous palonosetron for propofol-remifentanil-based anesthesia in breast and thyroid cancer surgery: a double-blind, randomized, controlled study [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundWe postulated that palonosetron, a novel antiemetic agent, might have the effect of alleviating injection pain from propofol and rocuronium.
Kye Hyeok Lee, Sung Kyu Rim, Ji Yeon Lee, So Young Lee, Su Nam Lee, Eun Ju Lee, Ji Heui Lee   +6 more
doaj   +1 more source

“ONDANSETRON VERSUS PALONOSETRON PARA EL MANEJO DE NÁUSEA Y VÓMITO POSTOPERATORIO EN COLECISTECTOMÍA LAPAROSCÓPICA EN ISSEMYM SATÉLITE” [PDF]

, 2013
Antecedentes: Las náuseas y vómitos postoperatorios (NVPO) son de los mayores problemas en anestesia, con una alta incidencia en cirugía laparoscópica.
Márquez Zapien, Cuitláhuac, Ramírez Romero, Salvador Iván   +1 more
core  

Epidemiology and treatment for thyroid cancer [PDF]

, 2011
The thyroid gland produces thyroid hormones which are important in the normal regulation of the metabolism of the body. Thyroid cancer is the most common malignancy of the endocrine system consisting of several subtypes like papillary carcinoma, and ...
Hima Bindu, A., Soumya, D., Srilatha, B.
core   +1 more source

Incidence and risk factor evaluation for postoperative nausea and vomiting in cesarean section under general anesthesia compared to the gynecologic surgery: A retrospective study

Journal of Obstetrics and Gynaecology Research, Volume 51, Issue 9, September 2025.
Abstract Aim This retrospective study sought to investigate the incidence of postoperative nausea and vomiting (PONV) and its associated risk factors in patients undergoing cesarean section under general anesthesia. Methods Patients who underwent cesarean section under general anesthesia or who underwent open gynecologic surgery were assigned to the OB
Su Yeon Kim, Seukyoung Hong, Jung‐Won Hwang, Sang‐Hwan Do, Hyo‐Seok Na   +4 more
wiley   +1 more source

Comparison of ondansetron, tropisetron, and palonosetron for the prevention of postoperative nausea and vomiting after middle ear surgery

Current Therapeutic Research, 2019
: Background: Postoperative nausea and vomiting (PONV) are 2 of the most frequent adverse effects of anesthesia. PONV prolongs hospital stays and also delays the recovery of patients.
Ahmet Aydin, MD, Mustafa Kaçmaz, MD, Adem Boyaci, MD   +2 more
doaj   +1 more source

Prophylactic Effect of Prefrontal Alternating Current Stimulation on Postoperative Sleep Disturbance in Patients Undergoing Gynecological Laparoscope: A Randomized, Double‐Blind, Sham‐Controlled Trial

CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
A single preventive session of prefrontal tACS significantly reduces the incidence of PSD on the first postoperative day in patients undergoing gynecological laparoscopic surgery. ABSTRACT Aims Postoperative sleep disturbance (PSD) is a common complication following surgical procedures.
Ni Du, Jin‐Jin Yang, Xin‐Yu Li, Zhi‐Hao Li, Kenji Hashimoto, Lei Lei, Jian‐Jun Yang   +6 more
wiley   +1 more source

Pre-therapy mRNA expression of TNF is associated with regimen-related gastrointestinal toxicity in patients with esophageal cancer: a pilot study [PDF]

, 2015
Author version made available following 12 month embargo from date of publication (27 March 2015) in accordance with publisher copyright policy.Purpose Esophageal cancer has a high mortality rate, and its multimodality treatment is often associated ...
Bowen, Joanne M, Game, Philip A, Hussey, Damian James, Irvine, Tanya S, Karapetis, Christos Stelios, Keefe, Dorothy M K, Kristaly, Kerry, Smith, Lorelle T, Tan, Thean Hsiang, Thompson, Sarah K, Tsykin, Anna, Watson, David Ian, White, Ian   +12 more
core   +1 more source