Results 61 to 70 of about 2,968 (201)

Feasibility of Using Deep Learning to Detect Hypoxemia During Painless Gastrointestinal Endoscopy Based on Facial Images

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
Objective To develop and validate deep learning (DL) and machine learning (ML) models based on preoperative facial images and structured clinical data for predicting hypoxemia during adult painless gastrointestinal endoscopy, addressing the limitations of subjective and data‐intensive prediction methods. Methods A total of 424 patients aged 18–80 years
Zhihu Yang, Fei Xing, Zhongyu Wang, Mingcui Qu, Yongchao Yao, Yafei Liu, Mingzhu Jing, Mingquan Xing, Jiaqi Chen, Dan Cheng, Na Xing, Ronald G. Pearl   +11 more
wiley   +1 more source

Effects of Inspired Oxygen Concentrations During Cardiopulmonary Bypass on the Pulmonary Function of Patients Undergoing a Modified Morrow Procedure via a Small Right Axillary Incision

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
Background Patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing minimally invasive modified Morrow procedure may be vulnerable to postoperative pulmonary dysfunction. During cardiopulmonary bypass (CPB), lung‐protective ventilation has been proposed, but the optimal inspired oxygen concentration under this strategy remains unclear ...
Linting Xu, Lixin Wang, Meijuan Yan, Hanwei Wei, Tian Jiang, Haozhou Wang, Jinchen Guo, Yong Cui, Chao Meng   +8 more
wiley   +1 more source

Impact of 5-HT₃ receptor antagonists on chemotherapy-induced nausea and vomiting: a retrospective cohort study

BMC Health Services Research, 2012
Background 1st generation 5-hydroxytryptamine receptor antagonists (5-HT3 RAs), and palonosetron, a 2nd generation 5-HT3 RA, are indicated for the prevention of chemotherapy (CT)-induced nausea and vomiting (CINV) associated with moderately (MEC) and ...
Lin Swu-Jane, Hatoum Hind T, Buchner Deborah, Cox David, Balu Sanjeev   +4 more
doaj   +1 more source

A double‐blind, randomized, multicenter phase 3 study of palonosetron vs granisetron combined with dexamethasone and fosaprepitant to prevent chemotherapy‐induced nausea and vomiting in patients with breast cancer receiving anthracycline and cyclophosphamide

Cancer Medicine, 2020
Purpose To investigate whether palonosetron is better than granisetron in preventing chemotherapy‐induced nausea and vomiting (CINV) in a three‐drug combination with dexamethasone and fosaprepitant (Fos) in patients with breast cancer who are placed on ...
Koji Matsumoto, Masato Takahashi, Kazuhiko Sato, Akihiko Osaki, Toshimi Takano, Yoichi Naito, Kazuo Matsuura, Kenjiro Aogi, Kimiko Fujiwara, Kenji Tamura, Motoi Baba, Shinya Tokunaga, Gen Hirano, Shigeru Imoto, Chieko Miyazaki, Kazuhiro Yanagihara, Chiyo K. Imamura, Yasutaka Chiba, Toshiaki Saeki   +18 more
doaj   +1 more source

Management of Propofol Infusion Pain: An Easy Task for Anesthetists

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
The aim of the present study is to lay out what the literature emphasizes regarding this topic, specifically the use of several drugs and their various doses, while explaining the mechanism of each agent, as well as discussing the comparison between lidocaine and these drugs, so that subsequent trials and investigators could rely on it when planning ...
Mohammed I. A. Ismail, Lou’i Al-Husinat, Omar Mar’ey, Ajwad Obeidat, Ahmad Bakkar, Qutaiba Manasrah, Ismail M. I. Ismail, Srijoni Sengupta   +7 more
wiley   +1 more source

An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

Pharmaceuticals, 2020
Cisplatin is widely used to treat various types of cancers, but it is often limited by nephrotoxicity. Here, we employed an integrated in silico and in vivo approach to identify potential treatments for cisplatin-induced nephrotoxicity (CIN).
Eri Wakai, Yuya Suzumura, Kenji Ikemura, Toshiro Mizuno, Masatoshi Watanabe, Kazuhiko Takeuchi, Yuhei Nishimura   +6 more
doaj   +1 more source

Use of Single‐Cell Data and scPagwas Analysis to Identify T Cell Subsets and Construct a Prognostic Model for Clear Cell Renal Cell Carcinoma

Human Mutation, Volume 2026, Issue 1, 2026.
Background Clear cell renal cell carcinoma (KIRC), the most prevalent pathological renal cell carcinoma (RCC) subtype, makes up approximately 75%–84% of total cases. KIRC is characterized by high heterogeneity, high metastasis rates, and a poor prognosis. Its incidence rate has continued to rise in recent years.
Xincheng Yi, Zongming Jia, Jixiang Wu, Siyu Wang, Yiqi Yu, Ying Kong, Xuefeng He, Yuhua Huang, Harleen Khatra   +8 more
wiley   +1 more source

A Systematic Review and Meta-Analysis of Intravenous Palonosetron in the Prevention of Chemotherapy-Induced Nausea and Vomiting in Adults

, 2011
Objectives. We performed a systematic review and meta-analysis to compare treatment effectiveness and adverse effects in cancer patients receiving chemotherapy with palonosetron to prevent chemotherapy-induced nausea and vomiting (CINV).
Jing Xiang, Zheng Liu Tao, Duan Xin, Zhou Likun, Ba Yi   +4 more
core   +1 more source

Agonists and antagonists induce different palonosetron dissociation rates in 5-HT3A and 5-HT3AB receptors [PDF]

, 2013
Palonosetron is a potent 5-HT3 receptor antagonist with a unique structure and some unusual properties. Here we explore the properties of palonosetron at heterologously expressed 5-HT3A and 5-HT3AB receptors.
Thompson, Andrew J., Lummis, Sarah C.R.
core   +1 more source

Comparison of ondansetron, tropisetron, and palonosetron for the prevention of postoperative nausea and vomiting after middle ear surgery

Current Therapeutic Research, 2019
: Background: Postoperative nausea and vomiting (PONV) are 2 of the most frequent adverse effects of anesthesia. PONV prolongs hospital stays and also delays the recovery of patients.
Ahmet Aydin, MD, Mustafa Kaçmaz, MD, Adem Boyaci, MD   +2 more
doaj   +1 more source