Results 71 to 80 of about 7,263 (276)
A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. [PDF]
, 2018 The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.Aapro, Aapro, Aapro, Ahmad, Alphin, Amin, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Angeli, Anttila, Appl, Armstrong, Ash, Atkinson, Axelsson, Babaoglu, Babkin, Baker, Bakker, Balaban, Barone, Batchelor, Benchaoui, Benchaoui, Bergeron, Bermudez, Bertaccini, Bertolini, Bhandari, Bhargava, Bianchi, Bignall, Birtley, Blair, Bockaert, Boisson, Booth, Borison, Borison, Borison, Borsook, Bountra, Boyd, Boyd, Boyle, Bradley, Brand, Brand, Briejer, Broad, Broad, Broad, Brogden, Brown, Bury, Bymaster, Camilleri, Camilleri, Carlsson, Carpenter, Carpenter, Cassidy, Cavella, Chakrabarti, Champion, Chandrasekharan, Chin, Chiu, Christie, Chu, Church, Clark, Clarke, Claude, Cooper, Coskun, Costall, Courvoisier, Crampton, Creytens, Currow, Danjoux, Darmani, Davis, de la Puente-Redondo, Diemunsch, Dietz, Dionne, Donovan, Douglas, Dumuis, Eglen, Emanuel, Ennis, Erspamer, Erspamer, Fairweather, Fangmann, Farmer, Faustini, Flaxman, Floczyk, Foubert, Fozard, Fozard, Fozard, Friend, Friend, Gaddum, Gardner, Gay, Gesztesi, Gibbs, Glaviano, Goddard, Golding, Golding, Gralla, Gralla, Greaves, Guttuso, Guttuso, Gylys, Gylys, Hale, Hamik, Harrington, Harris, Hasler, Hatcher, Hatcher, Hawthorn, Heckert, Helke, Henry, Herrstedt, Hesketh, Hill, Hill, Hocking, Holbrook, Holling, Holling, Holmes, Horn, Horn, Horn, Hornby, Hromatka, Huang, Huppert, Irwin, Isaacs, Ison, Jacoby, Janssen, Javid, Johnston, Jones, Jordan, Justin-Besancon, Justin-Besancon, Kail, Kanba, Keating, Kebabian, Keiser, Kennis, Kenward, Kim, King, Kirchner, Koch, Koch, Kojima, Kramer, Kranke, Kris, Kroeze, Kubo, Kundu, Lackner, Laird, Lal, Lang, Lau, Lau, Lee, Lees-Green, Leggio, Lembo, Lembo, Lentz, Lewis, Limebeer, Liu, Lu, Lu, Lundberg, López-Muñoz, Maceira, MacIntosh, Maggi, Markey, Marrinan, McEachern, McFarlane, McLean, McRitchie, Meek, Meltzer, Midani, Millan, Miller, Minami, Miner, Miner, Miner, Minton, Moertel, Money, Moreland, Moyer, Muchatuta, Napadow, Navari, Navari, Newton, Ng, Noble, Norton, O'Grady, Oman, Ortiz, Owens, Owyang, Palazzo, Parker, Parkinson, Pasricha, Peeters, Penta, Percie du Sert, Percie du Sert, Peroutka, Peroutka, Pickel, Pinder, Plezia, Prakash, Profet, Profet, Reason, Reason, Reavley, Reinhardt, Rennie, Revicki, Rhee, Rich, Ritter, Robinson, Rock, Rojas, Rojas, Rojas, Rosenfeld, Rupniak, Sallen, Saller, Sam, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Saria, Sawhney, Schmidt, Schulze-Delrieu, Schurig, Sclocco, Sigwald, Simoneau, Simons, Sirven, Slater, Smith, Smith, Sneader, Snider, Snyder, Soergel, Soto, Soukop, Spinks, Srivastava, Stadler, Stefanini, Stern, Stern, Stoltz, Sugino, Takatani, Tattersall, Tattersall, Thearle, Tonato, Tremblay, Tsuji, Tu, Ueno, Ueno, Vail, Van Sickle, Vincent, von Euler, von Euler, Wampler, Wang, Wang, Wang, Warr, Warr, Watson, Watson, Weerts, Weigel, Whitwam, Wong, Wyant, Yates, Zhong +349 morecore +3 more sourcesThe Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu +86 morewiley +1 more sourcePersonalized Estimate of Chemotherapy-Induced Nausea and Vomiting: Development and External Validation of a Nomogram in Cancer Patients Receiving Highly/Moderately Emetogenic Chemotherapy. [PDF]
, 2016 Chemotherapy-induced nausea and vomiting (CINV) is presented in over 30% of cancer patients receiving highly/moderately emetogenic chemotherapy (HEC/MEC).Chan, Alexandre, Chen, Likun, Hu, Zhihuang, Huang, Yan, Keefe, Dorothy, Liang, Wenhua, Ma, Yuxiang, Xue, Cong, Yang, Yunpeng, Zhang, Li, Zhao, Hongyun, Zhao, Yuanyuan +11 morecore +2 more sourcesFeasibility of an Intravenous Home Chemotherapy Intervention With Low‐Dose Cytarabine Administered by Parents (INTACTatHome)
Pediatric Blood &Cancer, Volume 72, Issue 11, November 2025.ABSTRACT
Background: Intravenous home chemotherapy (IHC) can reduce the frequency of hospital visits and positively affect the child's and the family's everyday life. Knowledge about IHC is needed to enhance evidence‐based provision and implementation. This study aimed to evaluate the feasibility of an IHC intervention.Louise Ingerslev Roug, Lisa Lyngsie Hjalgrim, Tenna Ruest Haarmark Nielsen, Martha Krogh Topperzer, Mary Jarden, Anders Tolver, Astrid Eliasen, Ayo Wahlberg, Rikke Thenning Michelsen, Helena Hansson +9 morewiley +1 more sourceTransversus abdominis plane block reduces remifentanil and propofol consumption, evaluated by closed-loop titration guided by bispectral index. [PDF]
, 2018 The present prospective, randomized, double-blind study aimed to determine the impact of transversus abdominis plane (TAP) block on propofol and remifentanil consumption, when administered by closed-loop titration guided by processed ...Jiang, Mei-Ru, Li, Tao, Liu, Gang-Gang, Liu, Hong, Ma, Jiahai, Sun, Qiao-Xia, Wang, Xue-Yan, Zhou, Jon +7 morecore Subchronic vortioxetine enhances cortical activity [PDF]
, 2016 Vortioxetine (VOR) is a multimodal antidepressant drug. VOR is a 5-HT3-R, 5-HT7-R and 5-HT1D-R antagonist, 5-HT1B-R partial agonist, 5-HT1A-R agonist, and serotonin transporter (SERT) inhibitor.Artigas, Francesc, Celada, Pau, Riga, Maurizio, Sánchez, Connie, Teruel-Martí, Vicent +4 morecore +1 more sourceSerotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities
MedComm, Volume 6, Issue 9, September 2025.This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT
Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu +7 morewiley +1 more sourceEffects of a self-management program on antiemetic-induced constipation during chemotherapy among breast cancer patients: a randomized controlled clinical trial. [PDF]
, 2016 Research on patient-reported outcomes indicates that constipation is a common adverse effect of chemotherapy, and the use of 5-hydroxytryptamine (serotonin; 5HT3) receptor antagonists aggravates this condition. As cancer patients take multiple drugs as a Arai, Hidenori, Hanai, Akiko, Ishiguro, Hiroshi, Mitani, Akira, Sozu, Takashi, Tsuboyama, Tadao, Tsuda, Moe +6 morecore +1 more source
