Results 91 to 100 of about 19,804 (212)

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry

Molecules, 2014
Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions ...
Emma-Dune Leriche, Marie Hubert-Roux, Carlos Afonso, Catherine M. Lange, Martin C. Grossel, Florian Maire, Corinne Loutelier-Bourhis   +6 more
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A Role for Nanoparticles in Treating Traumatic Brain Injury [PDF]

, 2019
Traumatic brain injury (TBI) is one of the main causes of disability in children and young adults, as well as a significant concern for elderly individuals.
Bony, Badrul Alam, Kievit, Forrest M.
core   +1 more source

l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury

Pharmaceutics, 2018
l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia ...
Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Rie Takashima, Masaki Morishita, Toshiyasu Sakane, Akira Yamamoto   +7 more
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Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods

Nano Biomedicine and Engineering, 2010
Herein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility.
Xueqing Zhang, Bifeng Pan, Kan Wang, Jing Ruan, Chenchen Bao, Hao Yang, Rong He, Daxiang Cui   +7 more
doaj   +1 more source

Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro

International Journal of Nanomedicine, 2015
Łukasz Uram,1 Magdalena Szuster,1 Aleksandra Filipowicz,2 Krzysztof Gargasz,3 Stanisław Wołowiec,3 Elżbieta Wałajtys-Rode4 1Bioorganic Chemistry Laboratory, Faculty of Chemistry, Rzeszow University of Technology, 2Cosmetology Department, University of ...
Uram Ł, Szuster M, Filipowicz A, Gargasz K, Wołowiec S, Wałajtys-Rode E   +5 more
doaj  

Elasticity of DNA and the effect of Dendrimer Binding

, 2013
Negatively charged DNA can be compacted by positively charged dendrimers and the degree of compaction is a delicate balance between the strength of the electrostatic interaction and the elasticity of DNA.
Maiti, Prabal K., Mogurampelly, Santosh, Nandy, Bidisha, Netz, Roland R.   +3 more
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Dendrimer Conjugation Enhances Tumor Penetration and Cell Kill of Doxorubicin in 3D Coculture Lung Cancer Models [PDF]

, 2020
Background: Doxorubicin (DOX) is a potent chemotherapeutic widely used for solid tumors (1). Despite high efficacy in 2D cell culture, DOX efficacy does not translate to in vivo lung cancer models (2).
Almuqbil, Rashed, Bielski, Elizabeth R., da Rocha, Sandro R. P., Durymanov, Mikhail, Heyder, Rodrigo S., Reineke, Joshua J.   +5 more
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Drug delivery system based on dendritic nanoparticles for enhancement of intravesical instillation

International Journal of Nanomedicine, 2017
Xuefeng Qiu,1,2,* Kai Cao,1,2,* Tingsheng Lin,1,2 Wei Chen,1 Ahu Yuan,2 Jinhui Wu,2 Yiqiao Hu,2 Hongqian Guo1 1Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University, Nanjing, China ...
Qiu X, Cao K, Lin T, Chen W, Yuan A, Wu J, Hu Y, Guo H   +7 more
doaj  

Synthesis and Characterization of Poly(Amidoamine) Dendrimers Encapsulated 198Au Nanoparticles [PDF]

, 2012
Brachytherapy or internal radiotherapy is one of many methods used for treatment of cancer. This modality requires an agent with radionuclides that emits α or β particle with a proper energy.
Kardono, L. B. (L), Kurniasih, D. (D), Mujinah, M. (Mujinah), Mutalib, A. (A), Pujiyanto, A. (A), Ramli, M. (M), Ritawidya, R. (R), Setiawan, S. (Setiawan), Witarti, W. (Witarti), Yanuar, A. (A)   +9 more
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Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer

Scientific Reports
The simultaneous administration of multiple drugs within identical nanocarriers to cancer cells or tissues can result in the effective action of drugs at reduced concentrations.
Ayuob Aghanejad, Shiva Kheiriabad, Maryam Ghaffari, Simin Namvar Aghdash, Neda Ghafouri, Jafar Ezzati Nazhad Dolatabadi, Hashem Andishmand, Michael R. Hamblin   +7 more
doaj   +1 more source