Results 71 to 80 of about 7,907 (187)

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Dendrimers bind antioxidant polyphenols and cisplatin drug.

PLoS ONE, 2012
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak, Philippe Bourassa, Jean-Sebastian Mandeville, Reza Sedaghat-Herati, Heidar-Ali Tajmir-Riahi   +4 more
doaj   +1 more source

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair, Syeda Zaira Batool, Mohamed H. Helal, Naila Afghan   +3 more
wiley   +1 more source

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity

Molecules, 2018
Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues.
Feng Gao, Ivan Djordjevic, Oleksandr Pokholenko, Haobo Zhang, Junying Zhang, Terry W. J. Steele   +5 more
doaj   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs

Molecules, 2018
The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu, Nannan Li, Yaochun Gao, Nan Li, Yifei Guo, Haitao Liu, Xi Chen, Chunyan Zhu, Zhengqi Dong, Akira Yamamoto   +9 more
doaj   +1 more source

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry

Molecules, 2014
Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions ...
Emma-Dune Leriche, Marie Hubert-Roux, Carlos Afonso, Catherine M. Lange, Martin C. Grossel, Florian Maire, Corinne Loutelier-Bourhis   +6 more
doaj   +1 more source

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates

International Journal of Pharmaceutical Investigation, 2014
The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela, Kumar, Pandurangan Dinesh, Kumar, Palanirajan Vijayaraj   +2 more
openaire   +3 more sources

Preparation and effect research of non-ionic demulsifiers for polymer-containing wastewater

Gongye shui chuli
A demulsification strategy based on hyperbranched non-ionic polyamide amine(h-PAMAM) was proposed to address the stability mechanism and demulsification bottleneck of polymer-containing wastewater systems, aiming to achieve dual goals of efficient oil ...
WANG Qingji, YANG Xueying, ZHANG Zejun, PEI Maochen, WANG Qinghong, SHI Quan, CHEN Chunmao   +6 more
doaj   +1 more source