Results 71 to 80 of about 19,804 (212)

One-Step Synthesis of Graphene Oxide-Polyamidoamine Dendrimer Nanocomposite Hydrogels by Self-Assembly [PDF]

open access: yes, 2016
Graphene oxide (GO)-polyamidoamine (PAMAM) dendrimer nanocomposite hydrogels were prepared through a one-step synthesis by mixing a GO suspension and a PAMAM solution at varying ratios of GO to PAMAM.
Chen, B., Piao, Y., Wu, T.
core   +2 more sources

Practical computational toolkits for dendrimers and dendrons structure design [PDF]

open access: yes, 2017
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok   +52 more
core   +3 more sources

Cationic PAMAM Dendrimers Disrupt Key Platelet Functions [PDF]

open access: yesMolecular Pharmaceutics, 2012
Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use. The dendritic structure features both modular synthetic control of molecular size and shape and presentation of multiple equivalent terminal groups.
Clinton F, Jones   +12 more
openaire   +2 more sources

Dendrimer-based selective autophagy-induction rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis.

open access: yesPLoS ONE, 2017
BackgroundCystic Fibrosis (CF) is a genetic disorder caused by mutation(s) in the CF-transmembrane conductance regulator (Cftr) gene. The most common mutation, ΔF508, leads to accumulation of defective-CFTR protein in aggresome-bodies.
Scott Mackenzie Brockman   +4 more
doaj   +1 more source

Bioconjugation of biotinylated PAMAM dendrons to avidin

open access: yesChemical Communications, 2007
The biotin-terminated PAMAM dendron has been synthesized and the asymmetric dendron used to modify the protein avidin via non-covalent bioconjugation.
Tao, L.   +6 more
openaire   +3 more sources

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling [PDF]

open access: yes, 2009
Atomistic molecular dynamics (MD) simulations of a G4-NH2 PAMAM dendrimer were carried out in aqueous solution using explicit water molecules and counterions (with the Dreiding III force field optimized using quantum mechanics).
Bryantsev, Vyacheslav S.   +3 more
core   +2 more sources

Self-assembly modulation in ionic PAMAM derivatives

open access: yesSoft Matter, 2014
The self-assembly behaviour both in the bulk and water of a series of amphiphilic dendrimers constituted by second generation PAMAM ionically functionalized with different amounts of myristic acid is shown here. The number of acids in the dendrimer determines the liquid-crystal properties and the structural parameters of their supramolecular ...
Hernández-Ainsa, Silvia   +5 more
openaire   +3 more sources

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

open access: yes, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani   +11 more
core   +2 more sources

A study on the hemocompatibility of dendronized chitosan derivatives in red blood cells

open access: yesDrug Design, Development and Therapy, 2015
Yanfang Zhou,1,* Jiemei Li,1,* Fang Lu,1 Junjie Deng,2 Jiahua Zhang,1 Peijie Fang,1 Xinsheng Peng,1 Shu-Feng Zhou3 1Guangdong Medical Universtity, Dongguan, Guangdong, People’s Republic of China; 2Department of Materials Science and Engineering ...
Zhou YF   +7 more
doaj  

Potential Use of Folate-polyethylene glycol (PEG)-Appended Dendrimer (G3) Conjugate with alpha-Cyclodextrin as DNA Carriers to Tumor Cells [PDF]

open access: yes, 2011
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with alpha-cyclodextrin (alpha-CyD) having an average degree of substitution of 2.4 of alpha-CyD (alpha-CDE) provided remarkable aspects as novel ...
Ayumi Yoshimitsu   +9 more
core   +1 more source

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