One-Step Synthesis of Graphene Oxide-Polyamidoamine Dendrimer Nanocomposite Hydrogels by Self-Assembly [PDF]
Graphene oxide (GO)-polyamidoamine (PAMAM) dendrimer nanocomposite hydrogels were prepared through a one-step synthesis by mixing a GO suspension and a PAMAM solution at varying ratios of GO to PAMAM.
Chen, B., Piao, Y., Wu, T.
core +2 more sources
Practical computational toolkits for dendrimers and dendrons structure design [PDF]
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok +52 more
core +3 more sources
Cationic PAMAM Dendrimers Disrupt Key Platelet Functions [PDF]
Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use. The dendritic structure features both modular synthetic control of molecular size and shape and presentation of multiple equivalent terminal groups.
Clinton F, Jones +12 more
openaire +2 more sources
BackgroundCystic Fibrosis (CF) is a genetic disorder caused by mutation(s) in the CF-transmembrane conductance regulator (Cftr) gene. The most common mutation, ΔF508, leads to accumulation of defective-CFTR protein in aggresome-bodies.
Scott Mackenzie Brockman +4 more
doaj +1 more source
Bioconjugation of biotinylated PAMAM dendrons to avidin
The biotin-terminated PAMAM dendron has been synthesized and the asymmetric dendron used to modify the protein avidin via non-covalent bioconjugation.
Tao, L. +6 more
openaire +3 more sources
PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling [PDF]
Atomistic molecular dynamics (MD) simulations of a G4-NH2 PAMAM dendrimer were carried out in aqueous solution using explicit water molecules and counterions (with the Dreiding III force field optimized using quantum mechanics).
Bryantsev, Vyacheslav S. +3 more
core +2 more sources
Self-assembly modulation in ionic PAMAM derivatives
The self-assembly behaviour both in the bulk and water of a series of amphiphilic dendrimers constituted by second generation PAMAM ionically functionalized with different amounts of myristic acid is shown here. The number of acids in the dendrimer determines the liquid-crystal properties and the structural parameters of their supramolecular ...
Hernández-Ainsa, Silvia +5 more
openaire +3 more sources
Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani +11 more
core +2 more sources
A study on the hemocompatibility of dendronized chitosan derivatives in red blood cells
Yanfang Zhou,1,* Jiemei Li,1,* Fang Lu,1 Junjie Deng,2 Jiahua Zhang,1 Peijie Fang,1 Xinsheng Peng,1 Shu-Feng Zhou3 1Guangdong Medical Universtity, Dongguan, Guangdong, People’s Republic of China; 2Department of Materials Science and Engineering ...
Zhou YF +7 more
doaj
Potential Use of Folate-polyethylene glycol (PEG)-Appended Dendrimer (G3) Conjugate with alpha-Cyclodextrin as DNA Carriers to Tumor Cells [PDF]
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with alpha-cyclodextrin (alpha-CyD) having an average degree of substitution of 2.4 of alpha-CyD (alpha-CDE) provided remarkable aspects as novel ...
Ayumi Yoshimitsu +9 more
core +1 more source

