Results 81 to 90 of about 7,907 (187)

Bioapplications of poly(amidoamine) (PAMAM) dendrimers in nanomedicine

Journal of Nanoparticle Research, 2014
Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies.
Pourianazar, Negar Taghavi, Mutlu, Pelin, Gunduz, Ufuk   +2 more
openaire   +2 more sources

Self-assembly modulation in ionic PAMAM derivatives

Soft Matter, 2014
The self-assembly behaviour both in the bulk and water of a series of amphiphilic dendrimers constituted by second generation PAMAM ionically functionalized with different amounts of myristic acid is shown here. The number of acids in the dendrimer determines the liquid-crystal properties and the structural parameters of their supramolecular ...
Hernández-Ainsa, Silvia, Fedeli, Elisabetta, Barberá, Joaquín, Marcos, Mercedes, Sierra, Teresa, Serrano, José Luis   +5 more
openaire   +3 more sources

Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro

International Journal of Nanomedicine, 2015
Łukasz Uram,1 Magdalena Szuster,1 Aleksandra Filipowicz,2 Krzysztof Gargasz,3 Stanisław Wołowiec,3 Elżbieta Wałajtys-Rode4 1Bioorganic Chemistry Laboratory, Faculty of Chemistry, Rzeszow University of Technology, 2Cosmetology Department, University of ...
Uram Ł, Szuster M, Filipowicz A, Gargasz K, Wołowiec S, Wałajtys-Rode E   +5 more
doaj  

l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury

Pharmaceutics, 2018
l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia ...
Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Rie Takashima, Masaki Morishita, Toshiyasu Sakane, Akira Yamamoto   +7 more
doaj   +1 more source

Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods

Nano Biomedicine and Engineering, 2010
Herein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility.
Xueqing Zhang, Bifeng Pan, Kan Wang, Jing Ruan, Chenchen Bao, Hao Yang, Rong He, Daxiang Cui   +7 more
doaj   +1 more source

Drug delivery system based on dendritic nanoparticles for enhancement of intravesical instillation

International Journal of Nanomedicine, 2017
Xuefeng Qiu,1,2,* Kai Cao,1,2,* Tingsheng Lin,1,2 Wei Chen,1 Ahu Yuan,2 Jinhui Wu,2 Yiqiao Hu,2 Hongqian Guo1 1Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University, Nanjing, China ...
Qiu X, Cao K, Lin T, Chen W, Yuan A, Wu J, Hu Y, Guo H   +7 more
doaj  

Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer

Scientific Reports
The simultaneous administration of multiple drugs within identical nanocarriers to cancer cells or tissues can result in the effective action of drugs at reduced concentrations.
Ayuob Aghanejad, Shiva Kheiriabad, Maryam Ghaffari, Simin Namvar Aghdash, Neda Ghafouri, Jafar Ezzati Nazhad Dolatabadi, Hashem Andishmand, Michael R. Hamblin   +7 more
doaj   +1 more source

Synthesis and Characterization of Poly(Amidoamine) Dendrimers Encapsulatd 198Au Nanoparticles

Atom Indonesia, 2012
Brachytherapy or internal radiotherapy is one of many methods used for treatment of cancer. This modality requires an agent with radionuclides that emits  or β particle with a proper energy.
R. Ritawidya1,2, A. Pujiyanto2,, Mujinah2, ,, Witarti2, , H. Setiawan2, , M. Ramli2, , D. Kurniasih2, , A. Yanuar1,, A. Mutalib2, L.B. Kardono3   +9 more
doaj  

Targeted delivery of polyamidoamine-paclitaxel conjugate functionalized with anti-human epidermal growth factor receptor 2 trastuzumab

International Journal of Nanomedicine, 2015
Pengkai Ma,1 Xuemei Zhang,1 Ling Ni,2 Jinming Li,2 Fengpu Zhang,1 Zheng Wang,1 Shengnan Lian,1 Kaoxiang Sun1 1School of Pharmacy, Yantai University, Yantai, Shandong Province, People’s Republic of China; 2State Key Laboratory of Long-acting and ...
Ma P, Zhang X, Ni L, Li J, Zhang F, Wang Z, Lian S, Sun K   +7 more
doaj  

Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer

Drug Design, Development and Therapy, 2015
Song Gao,1,* Jianfeng Li,2 Chen Jiang,2 Bo Hong,3 Bing Hao4,* 1Department of Clinical Laboratory, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 2Key Laboratory of Smart Drug Delivery, Ministry of Education, Department
Gao S, Li J, Jiang C, Hong B, Hao B
doaj