Results 101 to 110 of about 26,467 (310)

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Nanomaterials for Healthcare Biosensing Applications [PDF]

, 2019
In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field.
Altintas, Zeynep, Pirzada, Muqsit
core   +1 more source

Nano-Detoxification of Organophosphate Agents by PAMAM Derivatives

Journal of the Brazilian Chemical Society, 2015
For the first time, the adsorption of pesticides such as azinphos-methyl and methamidophos by polyamidoamine (PAMAM) derivatives was studied. Amine groups of PAMAM (G4 and G5) were functionalized with different biomolecules such as folic acid, coumarine, arginine, lysine, and asparagine.
Durán-Lara, Esteban F., Ávila-Salas, Fabian, Galaz, Sebastian, John, Amalraj, Maricán, Adolfo, Gutiérrez, Margarita, Nachtigall, Fabiane M., Gonzalez-Nilo, Fernando D., Santos, Leonardo S.   +8 more
openaire   +6 more sources

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

Advanced NanoBiomed Research, EarlyView.
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli, Sadman Sakib, Fabio Variola, Shan Zou   +3 more
wiley   +1 more source

Doxorubicin-Conjugated PAMAM Dendrimers for pH-Responsive Drug Release and Folic Acid-Targeted Cancer Therapy

Pharmaceutics, 2018
We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells.
Mengen Zhang, Jingyi Zhu, Yun Zheng, Rui Guo, Shige Wang, S. Mignani, A. Caminade, J. Majoral, Xiangyang Shi   +8 more
semanticscholar   +1 more source

Modulare Synthese dendritischer Oligo‐Glycerin‐Kationischer Tenside zur Steigerung der antibakteriellen Wirksamkeit

Angewandte Chemie, EarlyView.
Ein orthogonaler Klick‐Chemie‐Ansatz wurde verwendet, um eine Reihe von kationischen Tensiden zu synthetisieren. Die Ergebnisse zeigen, dass ein optimales Gleichgewicht zwischen positiven Ladungen und Hydrophobizität ein entscheidender Faktor für die Verbesserung der antibakteriellen Eigenschaften ist.
Natalie Hanheiser, Yuhang Jiang, Christian Zoister, Mathias Dimde, Katharina Achazi, Chuanxiong Nie, Yuanyuan Li, Rainer Haag, Abhishek K. Singh   +8 more
wiley   +1 more source

Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy

Pharmaceutical Research, 2019
Conjugation of nanocarriers with antibodies that bind to specific membrane receptors that are overexpressed in cancer cells enables targeted delivery.
M. Marcinkowska, M. Stańczyk, A. Janaszewska, Ewelina Sobierajska, A. Chworos, B. Klajnert-Maculewicz   +5 more
semanticscholar   +1 more source

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy [PDF]

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Bahrami, B., Bakhshaei, P., Ghalamfarsa, G., Hojjat-Farsangi, M., Jadidi-Niaragh, F., Mohammadnia-Afrouzi, M., Sadreddini, S., Yazdani, Y., Yousefi, M.   +8 more
core   +1 more source

Dendrimer-based selective autophagy-induction rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis.

PLoS ONE, 2017
BackgroundCystic Fibrosis (CF) is a genetic disorder caused by mutation(s) in the CF-transmembrane conductance regulator (Cftr) gene. The most common mutation, ΔF508, leads to accumulation of defective-CFTR protein in aggresome-bodies.
Scott Mackenzie Brockman, Manish Bodas, David Silverberg, Ajit Sharma, Neeraj Vij   +4 more
doaj   +1 more source

Synthesis of microporous silica nanoparticles to study water phase transitions by vibrational spectroscopy [PDF]

, 2019
Silica can take many forms, and its interaction with water can change dramatically at the interface. Silica based systems offer a rich tapestry to probe the confinement of water as size and volume can be controlled by various templating strategies and ...
Arriagada, Asay, Bechtel, Boreyko, Cerveny, Djojoputro, Dou, Enthaler, Fang, Fayer, Fumagalli, Huang, Jacobs, Joo, Knight, Kostko, Le Caër, Lee, Lin, Lin, Lin, Liu, Mei, Musat, Nagarajan, Nagata, Noy, Ostroverkhov, Peixinho, Peng, Qiao, Ren, Rosu-Finsen, Sharma, Sulpizi, Takei, Teng, Wan, Wan, Wang, Warring, Yang, Yi, Yi, Yu, Zhang, Zhang, Zhang, Zhao, Zhu   +49 more
core   +1 more source