Results 41 to 50 of about 49,152 (197)

Clinical Behaviour and Outcome of Pelvic Osteosarcoma in Dogs: A Retrospective Multicentre Analysis of 74 Cases (2007–2025)

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Although osteosarcoma is the most common primary bone tumour in dogs, involvement of the pelvic bones is rare. The aim of the present study was to describe clinical presentation, identify possible prognostic factors, and evaluate outcomes in dogs diagnosed with pelvic osteosarcoma.
Csilla Fejös, Felicitas Czichon, Maureen Griffin, Natalie Grillo, Quentin Fournier, Michelle L. Oblak, Mikaela Eng‐Toogood, Michael Kent, Isabelle Desmas‐Bazelle, Miriam Kleiter, Laura Marconato, Katie McNaught, Simona Vincenti, Carmit Chalfon, Petros Odatzoglou, Carla Rohrer Bley   +15 more
wiley   +1 more source

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

International Journal of Cancer, Volume 159, Issue 7, Page 1669-1685, 1 October 2026.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley, Fiona Caristo, Katrina Spilsbury, Sallie‐Anne Pearson, Peter Donovan, Michael D. Coory, Christopher B. Steer, Susan J. Jordan   +7 more
wiley   +1 more source

Pharmacokinetics of pamidronate in patients with bone metastases

, 1992
BACKGROUND: Pamidronate is a second-generation bisphosphonate used in the treatment of tumor-induced hypercalcemia and in the management of bone metastases from breast cancer, myeloma, or prostate cancer. The pharmacokinetics of pamidronate is unknown in
Hess, U., Bauer, J., Leyvraz, S., Ford, J. M., Hauffe, S., Flesch, G., Burckhardt, P.   +6 more
core   +1 more source

The Effects of Polyphenol, Tannic Acid, or Tannic Acid in Combination with Pamidronate on Human Osteoblast Cell Line Metabolism

Molecules, 2022
Background: This study investigates the effect of tannic acid (TA) combined with pamidronate (PAM) on a human osteoblast cell line. Methods: EC50 for TA, PAM, and different combination ratios of TA and PAM (25:75, 50:50, 75:25) were measured by 3-(4,5 ...
Hermizi Hapidin, Nor Munira Hashim, Mohamad Zahid Kasiram, Hasmah Abdullah   +3 more
doaj   +1 more source

Assessment of the Effect of Intravenous Pamidronate in the Treatment of Legg-Calve-Perthes Disease in Children

Novelty in Biomedicine
Background: Legg-Calvé-Perthes disease (LCPD) presents in childhood with idiopathic avascular necrosis of the femoral head(s), which can lead to disability and the need for corrective surgery at an early age.
Niloofar Shashaani, Reza Shiari, Hossein Sami, Khosro Rahmani, Mahmoud Hajipour, Vadood Javadi Parvaneh, Azadeh Zeinab Mirzaee   +6 more
doaj   +1 more source

Efficacy of pamidronate in children with chronic non-bacterial osteitis using whole body MRI as a marker of disease activity

Pediatric Rheumatology Online Journal, 2019
Background To study the response to pamidronate using whole body magnetic resonance imaging (WB-MRI) in children with chronic non-bacterial osteitis (CNO) in a tertiary health centre.
C. S. Bhat, M. Roderick, E. S. Sen, A. Finn, A. V. Ramanan   +4 more
doaj   +1 more source

Relationship between bisphosphonate use and risks of recurrence and mortality among hormone receptor–positive and triple‐negative breast cancer patients

Cancer, Volume 132, Issue 16, 15 August 2026.
Abstract Background Bisphosphonates (BPs) are routinely used as an adjuvant therapy for breast cancer to reduce the risk of bone recurrences given their anti‐resorptive effects on bones and antitumor characteristics. However, there remains limited evidence regarding their utility across different subtypes. Methods In this population‐based cohort study,
Liuye Huang, Linda S. Cook, Mei‐Tzu C. Tang, David R. Doody, Ulrike Peters, Wei Sun, Jeroen R. Huyghe, Kathleen E. Malone, Christopher I. Li   +8 more
wiley   +1 more source

Pamidronate treatment in acute vitamin D intoxication

, 2004
Management with glucocorticoid, high iv fluid saline intake, furosemide and calcitonin may not result in a favorable reduction of hypercalcemia and may cause several side effects in infants with acute vitamin D intoxication.
Davutoğlu, Mehmet, Bilici, Meki, Dikici, Bünyamin, Boşnak, Mehmet, Ece, Aydın, Gürkan, Fuat, Haspolat, Yusuf Kenan   +6 more
core   +1 more source

Pamidronate Attenuates Oxidative Stress and Energetic Metabolism Changes but Worsens Functional Outcomes in Acute Doxorubicin-Induced Cardiotoxicity in Rats

Cellular Physiology and Biochemistry, 2016
Background: Cardiotoxicity is the major side effect of doxorubicin. As mechanisms that are involved in cardiotoxicity are ambiguous, new methods for attenuating cardiotoxicity are needed.
Paula Bernardo de Carvalho, Andréa de Freitas Gonçalves, Patrícia Helena Correa Alegre, Paula Schmidt Azevedo, Meliza Goi Roscani, Carolina Marabesi Bergamasco, Pamela N. Modesto, Ana Angélica Fernandes, Marcos Ferreira Minicucci, Sergio Alberto Rupp Paiva, Leonardo Antonio, Mamede Zornoff, Bertha Furlan Polegato   +12 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source