Results 31 to 40 of about 48,475 (244)

Case report: Focal segmental glomerulosclerosis and nephrotic syndrome following treatment with pamidronate for calcitriol toxicity

Frontiers in Veterinary Science, 2022
ObjectiveThis study aimed to describe a case of glomerulosclerosis resulting in nephrotic syndrome following the administration of pamidronate disodium to treat clinical calcitriol toxicity in a dog.Case summaryA 12-week-old intact male Labrador ...
Katherine Ann Dawson, April Blong, Rebecca Walton   +2 more
doaj   +1 more source

Does pamidronate enhance the osteogenesis in mesenchymal stem cells derived from fibrous hamartoma in congenital pseudarthrosis of the tibia?

Bone Reports, 2016
Neurofibromatosis type 1 (NF1) is a commonly occurring genetic disorder in children. Mutation in the NF1 gene has its implication in poor osteoblastic capabilities.
Vrisha Madhuri, Smitha Elizabeth Mathew, Karthikeyan Rajagopal, Sowmya Ramesh, B Antonisamy   +4 more
doaj   +1 more source

Effectiveness and safety of pamidronate treatment in nonambulatory children with low bone mineral density [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose Nonambulatory pediatric patients may have low bone mineral density (BMD) and increased risk of pathologic fractures. Though bisphosphonate therapy is the mainstream medical intervention in these children, clinical data regarding this treatment ...
Myeongseob Lee, Ahreum Kwon, Kyungchul Song, Hae In Lee, Han Saem Choi, Junghwan Suh, Hyun Wook Chae, Ho-Seong Kim   +7 more
doaj   +1 more source

Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study [PDF]

Clinical and Experimental Pediatrics, 2022
Background Osteopenia and osteoporosis represent a prominent cause of morbidity in children with thalassemia. Multiple factors are responsible for the pathogenesis of bone loss in thalassemia, including diabetes, hypothyroidism, parathyroid gland ...
Mahmoud A. El-Hawy, Nagwan Y. Saleh
doaj   +1 more source

Pamidronate Attenuates Diastolic Dysfunction Induced by Myocardial Infarction Associated with Changes in Geometric Patterning

Cellular Physiology and Biochemistry, 2015
Background/Aims: The aim of this study was to evaluate the influence of pamidronate on ventricular remodeling after myocardial infarction. Methods: Male Wistar rats were assigned to four groups: a sham group, in which animals were submitted to simulated ...
Andréa F. Gonçalves, Luiz Henrique Congio, Priscila P. dos Santos, Bruna P. M. Rafacho, Bruna L. B. Pereira, Renan F. T. Claro, Nara A. Costa, Fernanda Chiuso-Minicucci, Paula S. Azevedo, Bertha F. Polegato, Katashi Okoshi, Elenize J. Pereira, Marina P. Okoshi, Sergio A. R. Paiva, Leonardo A. M. Zornoff, Marcos F. Minicucci   +15 more
doaj   +1 more source

Complications of pamidronate therapy in paediatric osteoporosis

Journal of Children's Orthopaedics, 2012
Purpose Pamidronate, used for the treatment of paediatric osteoporosis, reduces the fracture rate and improves ambulatory status. Intravenous pamidronate therapy has known complications which have not been stratified based on its dose and distribution ...
Sanjay K. Chilbule, Vrisha Madhuri
doaj   +1 more source

Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

Frontiers in Endocrinology, 2019
Not only has pamidronate been shown to prevent inflammation associated bone resorption following burn injury, it also reduces protein breakdown in muscle.
Fabrizio Pin, Fabrizio Pin, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Lynda F. Bonewald, Lynda F. Bonewald, Lynda F. Bonewald, Gordon L. Klein   +10 more
doaj   +1 more source

Metaphyseal bands in osteogenesis imperfecta

Indian Journal of Radiology and Imaging, 2010
An increasing number of patients with osteogenesis imperfecta are undergoing pamidronate therapy to prevent the incidence of fragility fractures. The authors herein report a child aged 3 years who received five cycles of pamidronate, resulting in ...
Suresh S, Thomas John
doaj   +3 more sources

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

International Journal of Cancer, EarlyView.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley, Fiona Caristo, Katrina Spilsbury, Sallie‐Anne Pearson, Peter Donovan, Michael D. Coory, Christopher B. Steer, Susan J. Jordan   +7 more
wiley   +1 more source

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, EarlyView.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source