Results 31 to 40 of about 49,152 (197)

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott, Eugene Moylan, Maree Colosimo, Giles Stratton, Thomas Chiu, Mahsa H. Kouhkamari, Maureen Hitschfeld, Jessica Michie, Richard De Boer   +8 more
wiley   +1 more source

A comparison of the responses to the intact pamidronate integrated model with those to the blocked pamidronate integrated model after multi-dose pamidronate administration.

, 2012
(a) The active osteoclast after multi-dose pamidronate administration. (b) The bone volume after multi-dose pamidronate administration. (c) The MM-cell density after multi-dose pamidronate administration. Blue: the intact model; Black: the blocked model.
Yan Wang (15435), Bo Lin (116835)
core   +1 more source

Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski, Rachel Dear, Sanjeev Kumar, Hilary Martin, Dhanusha Sabanathan, Stephen J. Luen, Belinda Yeo   +6 more
wiley   +1 more source

Bone density, fractures and the associated factors in iranian children and adolescent with Osteogenesis Imperfecta

BMC Pediatrics, 2021
Backround Osteogenesis imperfecta(OI) is a frequent bone fragility disorder in children. The purpose of this study was to assess the BMD and Vitamin D level in children with OI in southern Iran. Method This case-control study was conducted on 23 children,
Pooran Mohsenzade, Anis Amirhakimi, Naser Honar, Forough Saki, Gholam Hossein Ranjbar Omrani, Mohammadhosein Dabbaghmanesh   +5 more
doaj   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Hypercalcemia in a Patient With Spinal Tuberculosis and Aspergillus Co‐Infection: A Case‐Report [PDF]

Immun Inflamm Dis
ABSTRACT Background Tuberculosis (TB), one of the leading infectious causes of mortality worldwide, may disseminate hematogenously and result in extrapulmonary manifestations. Spinal tuberculosis (ST) is an uncommon but serious form of extrapulmonary TB.
Parsa N, Amlelshahbaz A, Soltani H.
europepmc   +2 more sources

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

Oral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra, Gómez Hernández Kevin Andrew, Cabrera del Cid María Fernanda, Jerez Robalino James Philippe   +3 more
wiley   +1 more source

Use of disodium pamidronate bisphosphonate in patients with bone metastases of lung cancer [PDF]

Vojnosanitetski Pregled, 2002
Disodium pamidronate (Aredia®), a drug of the bisphosphonate group, was administered to 20 patients with pains in the bones due to secondary deposits of lung cancer.
Ranković Boško, Mrđa Vladimir
doaj   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis, Davi Araújo, Asaf Wilensky, Juliana Girón Bastidas, Stella Alimperti, Flavia Pirih   +5 more
wiley   +1 more source