Results 11 to 20 of about 51,672 (208)

Complete Response to the Combination of Immunotherapy and Targeted Therapy in Stage IV Nasal Adenocarcinoma of a Dog: A Case Report. [PDF]

Vet Med Sci
The combination therapy of anti‐PD‐1 and TOC showed good therapeutic effects in this case of canine nasal adenocarcinoma, underscoring the potential of combining immunotherapy with targeted therapy in cases where single‐agent treatments fail. Combination therapy may enhance tumour growth inhibition by regulating the tumour immune microenvironment.
Hu Y, Shi W, Xie J, Wang S, Feng J, Su Y, Li G.   +6 more
europepmc   +2 more sources

Advanced Platelet-Rich Fibrin in Surgical Management of Medication-Related Osteonecrosis of the Jaw: A Prospective Case Series Study. [PDF]

Clin Exp Dent Res
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a severe complication associated with antiresorptive or antiangiogenic therapy. Surgical debridement is the mainstay of treatment for moderate to advanced disease, while adjunctive regenerative approaches such as advanced platelet‐rich fibrin (A‐PRF) may enhance soft tissue ...
Hajdari B, Morina LL, Gashi G, Dobra G, Salihu B, Bimbashi V.   +5 more
europepmc   +2 more sources

Clinical and biochemical response to neridronate treatment in a patient with osteoporosis-pseudoglioma syndrome (OPPG) [PDF]

, 2017
Osteoporosis-pseudoglioma syndrome (OPPG) is a rare autosomal recessive syndrome characterized by juvenile-onset osteoporosis and ocular abnormalities due to a low-density lipoprotein receptor-related protein 5 (LRP5) gene mutation.
Celli, L, Celli, M., D'Alfonso, Y, D'Eufemia, P, Febbo, A, Persiani, P, Turchetti, A., Zambrano, A   +7 more
core   +1 more source

Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra. [PDF]

, 2017
Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in
Barbareschi, Cassel, Colina, Firinu, Firinu, Laasonen, Nast, Nguyen, Wendling, Zaba   +9 more
core   +1 more source

Pamidronate

, 2006
europepmc   +2 more sources

Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents [PDF]

, 2014
Bone metastases in advanced cancer frequently cause painful complications that impair patient physical activity and negatively affect quality of life. Pain is often underreported and poorly managed in these patients.
A Kretzschmar, A Mañas, A Wardley, AT Stopeck, C Langer, C Logothetis, Charles S. Cleeland, CI Ripamonti, CJ Logothetis, CS Cleeland, CS Cleeland, D Henry, D Patrick, DH Henry, DL Patrick, Donald L. Patrick, DS Ernst, E Basch, E Chow, F Saad, F Saad, G Apolone, G Cartenì, G Storto, GN Hortobagyi, GN Hortobagyi, HI Scher, JJ Body, JJ Body, K Altundag, K Fizazi, K Harris, Katarina Öhrling, KC Chung, KP Weinfurt, KP Weinfurt, L Atahan, L Costa, L Fallowfield, Lesley Fallowfield, LS Matza, LS Rosen, LS Rosen, LS Rosen, M Huisman, M Martin, M Tomblyn, MG Lam, MJ Fisch, N Kohno, N Takeda, P Hoskin, P Hoskin, R Moos von, R Moos von, Rachel Wei, RE Coleman, RE Coleman, RE Coleman, RH Dworkin, RL Theriault, Roger von Moos, S Deandrea, S Nilsson, S Vadhan-Raj, SD Mathias, T Kijima, V Vassiliou, V Vassiliou, Yi Qian   +69 more
core   +1 more source

Pamidronate Disodium for Palliative Therapy of Feline Bone-Invasive Tumors

Veterinary Medicine International, 2014
This study sought to quantify in vitro antiproliferative effects of pamidronate in feline cancer cells and assess feasibility of use of pamidronate in cats by assessing short-term toxicity and dosing schedule in cats with bone-invasive cancer.
Jackie M. Wypij, David A. Heller
doaj   +1 more source

Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes. [PDF]

, 2017
Nitrogen-containing bisphosphonates (N-BPs) are the most widely used anti-resorptive agents in the treatment of bone-related diseases. N-BPs inhibit bone resorption by specifically targeting osteoclasts, bone-resorbing cells.
Kang, Mo K, Kim, Reuben H, Lee, Rachel S, Park, No-Hee, Shin, Ki-Hyuk, Sohn, Suhjin   +5 more
core   +1 more source

Dramatic pain relief and resolution of bone inflammation following pamidronate in 9 pediatric patients with persistent chronic recurrent multifocal osteomyelitis (CRMO)

Pediatric Rheumatology Online Journal, 2009
Background Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory, non-infectious osteopathy that affects predominantly patients ≤ 18 years of age. There is no uniformly effective treatment.
Reslan Walid, Kaura Deepak, Wei Xingchang, Miettunen Paivi MH, Aguirre Alberto, Kellner James D   +5 more
doaj   +1 more source

Efficacy and safety of intravenous pamidronate infusion for treating osteoporosis in children and adolescents [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2021
Purpose Osteoporosis is a skeletal disorder characterized by reduced bone mass that results in increased risk of fractures. Pediatric osteoporosis can be caused by monogenic diseases, chronic diseases, and/or their treatment.
Ji-Hee Yoon, Yunha Choi, Yena Lee, Han-Wook Yoo, Jin-Ho Choi   +4 more
doaj   +1 more source