Results 21 to 30 of about 49,152 (197)

Case report: Focal segmental glomerulosclerosis and nephrotic syndrome following treatment with pamidronate for calcitriol toxicity

Frontiers in Veterinary Science, 2022
ObjectiveThis study aimed to describe a case of glomerulosclerosis resulting in nephrotic syndrome following the administration of pamidronate disodium to treat clinical calcitriol toxicity in a dog.Case summaryA 12-week-old intact male Labrador ...
Katherine Ann Dawson, April Blong, Rebecca Walton   +2 more
doaj   +1 more source

Treatment of experimental renal osteodystrophy with pamidronate [PDF]

, 2008
We evaluated the effects of the bisphosphonate pamidronate on bone histomorphometry, structure and strength in male rats with uninephrectomy or with chronic renal disease induced by 5/6 nephrectomy.
Jokihaara, Jarkko, Mustonen, Jukka T., Turner, Russell T., Pörsti, Ilkka H., Jolma, Pasi M., Kannus, Pekka, Järvinen, Teppo L.N., Saha, Heikki H.T., Sievänen, Harri, Iwaniec, Urszula T., Kööbi, Peeter   +10 more
core   +1 more source

Does pamidronate enhance the osteogenesis in mesenchymal stem cells derived from fibrous hamartoma in congenital pseudarthrosis of the tibia?

Bone Reports, 2016
Neurofibromatosis type 1 (NF1) is a commonly occurring genetic disorder in children. Mutation in the NF1 gene has its implication in poor osteoblastic capabilities.
Vrisha Madhuri, Smitha Elizabeth Mathew, Karthikeyan Rajagopal, Sowmya Ramesh, B Antonisamy   +4 more
doaj   +1 more source

Effectiveness and safety of pamidronate treatment in nonambulatory children with low bone mineral density [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose Nonambulatory pediatric patients may have low bone mineral density (BMD) and increased risk of pathologic fractures. Though bisphosphonate therapy is the mainstream medical intervention in these children, clinical data regarding this treatment ...
Myeongseob Lee, Ahreum Kwon, Kyungchul Song, Hae In Lee, Han Saem Choi, Junghwan Suh, Hyun Wook Chae, Ho-Seong Kim   +7 more
doaj   +1 more source

Pamidronate Attenuates Diastolic Dysfunction Induced by Myocardial Infarction Associated with Changes in Geometric Patterning

Cellular Physiology and Biochemistry, 2015
Background/Aims: The aim of this study was to evaluate the influence of pamidronate on ventricular remodeling after myocardial infarction. Methods: Male Wistar rats were assigned to four groups: a sham group, in which animals were submitted to simulated ...
Andréa F. Gonçalves, Luiz Henrique Congio, Priscila P. dos Santos, Bruna P. M. Rafacho, Bruna L. B. Pereira, Renan F. T. Claro, Nara A. Costa, Fernanda Chiuso-Minicucci, Paula S. Azevedo, Bertha F. Polegato, Katashi Okoshi, Elenize J. Pereira, Marina P. Okoshi, Sergio A. R. Paiva, Leonardo A. M. Zornoff, Marcos F. Minicucci   +15 more
doaj   +1 more source

Bisphosphonate treatment in primary breast cancer: results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer

, 2008
PURPOSE AND PATIENTS: During the period from January 1990 to January 1996 a total of 953 patients with lymph node negative primary breast cancer were randomised to oral pamidronate (n=460) 150 mg twice daily for 4 years or no adjuvant pamidronate (n=493)
Ejlertsen, B., Jensen, M.B., Bjerregaard, B., Ewertz, M., Kristensen, B., Andersen, J., Cold, S., Lindman, H., Kamby, C., Mouridsen, H.T., Edlund, P., Nordenskjold, B., Bergh, J.   +12 more
core   +3 more sources

Complications of pamidronate therapy in paediatric osteoporosis

Journal of Children's Orthopaedics, 2012
Purpose Pamidronate, used for the treatment of paediatric osteoporosis, reduces the fracture rate and improves ambulatory status. Intravenous pamidronate therapy has known complications which have not been stratified based on its dose and distribution ...
Sanjay K. Chilbule, Vrisha Madhuri
doaj   +1 more source

Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

Frontiers in Endocrinology, 2019
Not only has pamidronate been shown to prevent inflammation associated bone resorption following burn injury, it also reduces protein breakdown in muscle.
Fabrizio Pin, Fabrizio Pin, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Andrea Bonetto, Lynda F. Bonewald, Lynda F. Bonewald, Lynda F. Bonewald, Gordon L. Klein   +10 more
doaj   +1 more source

Metaphyseal bands in osteogenesis imperfecta

Indian Journal of Radiology and Imaging, 2010
An increasing number of patients with osteogenesis imperfecta are undergoing pamidronate therapy to prevent the incidence of fragility fractures. The authors herein report a child aged 3 years who received five cycles of pamidronate, resulting in ...
Suresh S, Thomas John
doaj   +3 more sources

Pamidronate for the treatment of osteoporosis secondary to chronic cholestatic liver disease in Wistar rats

Brazilian Journal of Medical and Biological Research, 2012
Osteoporosis is a major complication of chronic cholestatic liver disease (CCLD). We evaluated the efficacy of using disodium pamidronate (1.0 mg/kg body weight) for the prevention (Pr) or treatment (Tr) of cholestasis-induced osteoporosis in male Wistar
F.A. Pereira, R. Mattar, I. Facincani, H.L.A. Defino, L.N.Z. Ramalho, V. Jorgetti, J.B. Volpon, F.J.A. de Paula   +7 more
doaj   +2 more sources