Results 131 to 140 of about 823,779 (195)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold, Chia Wei Cheah, Rathna Devi Vaithilingam   +2 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

MicroRNA 160 controls the auxin response factor–class III peroxidase module and couples salicylic acid and redox signaling networks in the potato hypersensitive response to potato virus Y

New Phytologist, EarlyView.
miR160 links salicylic acid, auxin, and redox signaling with the growth–defense trade‐off in the potato hypersensitive response to potato virus Y. Summary Hypersensitive response (HR) is an effector‐triggered immune response leading to pathogen restriction and local cell death.
Maja Križnik, Tjaša Lukan, Maja Zagorščak, Anna Coll Rius, Karmen Pogačar, Nastja Marondini, Katja Stare, Valentina Levak, Jitka Široká, Ondřej Novák, Aleš Kladnik, Kristina Gruden   +11 more
wiley   +1 more source

Cell wall integrity and elicitor peptide signaling modulate jasmonic acid‐mediated camalexin production in Arabidopsis

New Phytologist, EarlyView.
Model of the cell wall damage (CWD)‐responsive signaling network leading to camalexin biosynthesis. Summary Plant cell walls constitute dynamic barriers that are essential for defense against pathogens. Beyond a structural role in blocking pathogen infection, innate mechanisms monitor cell wall integrity (CWI) in Arabidopsis thaliana and trigger local ...
Richard Noi Morton, Lian Fleischberger, Joy Debnath, David Biermann, Susanne Mühlbauer, Ahalya Rajendran, Hans‐Henning Kunz, Julien Gronnier, Nora Gigli Bisceglia, Timo Engelsdorf   +9 more
wiley   +1 more source

ZmPHO2‐Mediated Phosphorus Homeostasis Modulates PAMP‐Triggered Immunity and Disease Resistance in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Maize production is influenced by both macronutrient‐driven growth and resistance to various abiotic and biotic stresses. While phosphorus (P) is essential for maize growth and productivity, its role in maize immunity remains elusive. Here, we characterized a maize lesion mimic mutant, les33, which exhibits enhanced resistance to southern corn
Mengyao Chen, Chenyang Zhao, Wenli Zhang, Xiaorui Men, Bingyang Wang, Wanying Lv, Guo Li, Ye Xing, Jinjun Tian, Ying Wang, Jie Gao, Na Zhang, Ying Zhang, Yuying Wu, Xingbin Wang, Jie Zhang, Cuilan Shi, Xiaohuan Mu, Liping Xu, Yanwen Yu, Yihao Zhang, Kangxu Zhang, Qun Wang, Junqiang Ding, Hongen Liu, Jihua Tang, Jiankun Li, Mingyue Gou   +27 more
wiley   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Leaf Structure and Hormonal Balance Modulate Host‐Specificity and Pathogenicity of Botrytis cinerea

Plant, Cell &Environment, EarlyView.
ABSTRACT Botrytis cinerea, a highly successful necrotrophic fungal plant pathogen, demonstrates a remarkably broad host range, yet the precise factors governing its host specificity and its ability to coexist non‐pathogenically with plants remain unclear. This study systematically assessed host preference in a series of B. cinerea agricultural isolates,
Gautam Anand, Chen Benoni, Meirav Leibman‐Markus, Rupali Gupta, Iftah Marash, Loida Tejada, Tali Dolgov, Dalia Rav‐David, Ondřej Plíhal, Ondřej Novák, Maya Kleiman, Yigal Elad, Maya Bar   +12 more
wiley   +1 more source

Perturbation of Spermine Homoeostasis Uncouples Hypersensitive Cell Death From Systemic Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Polyamines are key regulators of plant stress responses, yet their contribution to coordinating local immune responses with systemic immunity remains poorly understood. Here, we investigated how spermine (Spm) homeostasis influences local and systemic defence responses in Arabidopsis thaliana following inoculation with Pseudomonas syringae pv.
Jiaqi Zhao, Kostadin E. Atanasov, Olga Jauregui, Rubén Alcázar   +3 more
wiley   +1 more source