Results 81 to 90 of about 686,190 (235)

Shared signals, different fates: Calcium and ROS in plant PRR and NLR immunity

open access: yesCell Reports
Summary: Lacking an adaptive immune system, plants rely on innate immunity comprising two main layers: PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI), both utilizing Ca2+ influx and reactive oxygen species (ROS) for signaling.
Chanusha Weralupitiya   +2 more
doaj   +1 more source

Lflg22, a Pathogen-Associated Molecular Pattern (PAMP) of Candidatus Liberibacter asiaticus, initiated differential PAMP-Triggered Immunity (PTI) in Grapefruit and Sun Chu Sha [PDF]

open access: yes, 2014
‘Duncan’ Grapefruit (Citrus paradisi Macf.) and ‘Sun Chu Sha’ mandarin (C. reticulalta Blanco) represent two citrus genotypes that have different levels of tolerance to citrus greening or huanglongbing (HLB), a bacterial disease caused by Candidatus ...
Febres, Vicente J.   +3 more
core   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

open access: yesAdvanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu   +7 more
wiley   +1 more source

Different Pathogen Defense Strategies in Arabidopsis: More than Pathogen Recognition

open access: yesCells, 2018
Plants constantly suffer from simultaneous infection by multiple pathogens, which can be divided into biotrophic, hemibiotrophic, and necrotrophic pathogens, according to their lifestyles.
Wei Zhang   +5 more
doaj   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

open access: yesAdvanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou   +4 more
wiley   +1 more source

Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

open access: yesAdvanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou   +7 more
wiley   +1 more source

Development of a Pseudomonas syringae–Arabidopsis Suspension Cell Infection System for Investigating Host Metabolite-Dependent Regulation of Type III Secretion and Pattern-Triggered Immunity

open access: yesMolecular Plant-Microbe Interactions, 2019
The importance of pattern-triggered immunity (PTI) in plant defense has been clearly established through genetic studies of mutants lacking functional pattern recognition receptors (PRRs) and signaling components downstream of PRR activation.
Qing Yan   +2 more
doaj   +1 more source

Characterization of a novel bacterial PAMP - elongation factor Tu - and its role in "Arabidopsis thaliana" defense and immunity [PDF]

open access: yes, 2005
The discrimination of self and nonself is a primary challenge for all living organisms to detect microbial invasion and to protect and defend against the invader.
Kunze, Gernot Ulrich
core   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li   +4 more
wiley   +1 more source

Linking Endosomal Traffic and PAMP-triggered Immunity in Plants [PDF]

open access: yes, 2009
One of the first layers of active defense in plant-microbe interactions is based upon the recognition of pathogen associated molecular patterns (PAMPs). Although biochemically well studied, components of PAMP signaling await to be identified. Furthermore,
Salomon, Susanne Anna   +2 more
core   +1 more source

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