Results 91 to 100 of about 23,370 (263)

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei   +9 more
wiley   +1 more source

Assessing ChatGPT for taxonomic and floristic studies

open access: yesNordic Journal of Botany, EarlyView.
The advancement of biological sciences has long been closely linked to technological progress. ChatGPT, a generative artificial intelligence chatbot capable of producing human‐like conversational responses, has recently attracted attention as a potential support tool for scientific research.
Mykyta Peregrym   +7 more
wiley   +1 more source

A national crop wild relative checklist for Zimbabwe reveals edible crop wild relative diversity of regional and global importance

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Crop wild relatives (CWR) in Zimbabwe are reservoirs of beneficial agronomic traits, yet they remain under‐documented and poorly conserved. This study developed Zimbabwe's first national CWR checklist based on a conceptual framework combining floristic, ecological and ethnobotanical data, revealing over 2700 taxa, with nearly 1000 edible species ...
Kudakwashe Mutasa   +3 more
wiley   +1 more source

On PAMPs and DAMPs

open access: yesJournal of Innate Immunity, 2016
Heiko Herwald, Arne Egesten
openaire   +2 more sources

PAMPS PolyHIPEs

open access: yes
Opis vira z dne 9. 12. 2025.
Kovačič, Sebastijan, Vladušić, Roko
openaire   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

open access: yesSmall, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

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