Results 91 to 100 of about 27,901 (286)

Molecular evolution of proadrenomedullin N-terminal 20 peptide (PAMP):evidence for gene co-option

, 2006
Posttranslational processing of proadrenomedullin generates two biologically active peptides, adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP).
Martínez, Alfredo, Cuttitta, Frank, Bengoechea, José Antonio; id_orcid   +2 more
core   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

Luciferase-mediated assay to detect the PAMP-triggered gene expression in transgenic Nicotiana benthamiana

Plant Signaling & Behavior
Luciferase is one of the bioluminescence-producing agents, which was widely used as a reporter enzyme for constructing bioassay systems to study gene expression with high accuracy and within a broad dynamic spectrum.
Ola Barakat, Fushuang Zhang, Mengzhu Zeng, Yuanchao Wang   +3 more
doaj   +1 more source

Pamp, Fred

, 1941
Body cremated.
Carey Hand Funeral Home
core  

Proadrenomedullin N-terminal 20 peptide (PAMP) stimulates aldosterone secretion by the intact rat adrenal glomerulosa by a cAMP-dependent mechanism [PDF]

, 1998
Preproadrenomedullin, the precursor of proadrenomedullin N-terminal 20 peptide (PAMP), is produced by rat zona glomerulosa cells. The actions of PAMP on the rat adrenal have been investigated.
Hinson, J.P., L.M. Thomson, J.P. Hinson, Thomson, L.M., Kapas, S., S. Kapas   +5 more
core   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

PAMP: an automated high-resolution image analysis pipeline for life cycle quantitative morphological profiling in filamentous fungi

Mycology
Morphological development in filamentous fungi critically impacts nutrient and oxygen transfer, broth rheology, and metabolite production during submerged fermentation.
Meiling Chen, Haijie Ding, Yuxiang Zhang, Zhimin Li, Xiaomei Zheng, Ping Zheng, Jibin Sun   +6 more
doaj   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

PORTABLE ACOUSTIC MONITORING PACKAGE (PAMP) [PDF]

, 2004
The Portable Acoustic Monitoring Package (PAMP) has been designed to record and monitor the acoustic signal in natural gas transmission lines. In particular the three acoustic signals associated with a line leak.
Browning, Patrick, Loth, John L., Morris, Gary J., Palmer, George M., Guiler, Richard   +4 more
core   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

Advanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou, Yuanjiang Cui, Chaoqing Ding, Qian Qian, Deyong Ren   +4 more
wiley   +1 more source