Results 1 to 10 of about 124,614 (151)

(Pro)renin receptor involves in myocardial fibrosis and oxidative stress in diabetic cardiomyopathy via the PRR–YAP pathway

open access: yesScientific Reports, 2021
(Pro)renin receptor (PRR) and Yes-associated protein (YAP) play an important role in cardiovascular diseases. However, the role of PRR–YAP pathway in the pathogenesis of DCM is also not clear. We hypothesized that PRR–YAP pathway may promote pathological
Min Yang, Jing Chen, Bo Dong
exaly   +2 more sources

Single cell analysis of human RAD18-dependent DNA post-replication repair by alkaline bromodeoxyuridine comet assay. [PDF]

open access: yesPLoS ONE, 2013
Damage to DNA can block replication progression resulting in gaps in the newly synthesized DNA. Cells utilize a number of post-replication repair (PRR) mechanisms such as the RAD18 controlled translesion synthesis or template switching to overcome the ...
Mónika Mórocz   +4 more
doaj   +4 more sources

Comparative Safety of GLP-1 Receptor Agonists Across Gastrointestinal, Renal and Pancreatic Systems [PDF]

open access: yesPharmaceuticals
Objectives: to assess the safety profile of Gastrointestinal (GIT), renal, and pancreatic effects of GLP-1 and dual receptor agonists. Methods: Disproportionality analyses were performed on FDA Adverse Event Reporting System (FAERS) data following each ...
Hala Shokr, Mohamed Mekkawy, Ali Hindi
doaj   +2 more sources

Overweight and obesity in south central Uganda: A population-based study.

open access: yesPLOS Global Public Health, 2022
Obesity is a rapidly growing global health challenge, but there are few population-level studies from non-urban settings in sub-Saharan Africa. We evaluated the prevalence of overweight (body mass index (BMI)>25 kg/m2), obesity (BMI>30 kg/m2), and ...
Adeoluwa Ayoola   +14 more
doaj   +2 more sources

(Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-β1/SMAD3 PathwaySummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Activation of the (pro)renin receptor (PRR) up-regulates the expression of profibrotic genes in the kidney and heart. We aimed to investigate the role of PRR in hepatic fibrogenesis.
Yun-Cheng Hsieh   +10 more
doaj   +1 more source

Effect of Pink Rock Rose Extract with or Without Ascorbic Acid and Sodium Ascorbate for the Preservation of Ready-to-Eat Frankfurter Type Sausages

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2022
This study aimed to determine the effect of pink rock rose extract (PRR) with or without ascorbic acid and sodium ascorbate for improving the shelf life of sausages.
Ayça Gedikoğlu   +4 more
doaj   +1 more source

Sensor Sensibility—HIV-1 and the Innate Immune Response

open access: yesCells, 2020
Innate immunity represents the human immune system’s first line of defense against a pathogenic intruder and is initiated by the recognition of conserved molecular structures known as pathogen-associated molecular patterns (PAMPs) by specialized ...
Xin Yin   +6 more
doaj   +1 more source

Effects of (Pro)renin Receptor on Diabetic Cardiomyopathy Pathological Processes in Rats via the PRR-AMPK-YAP Pathway

open access: yesFrontiers in Physiology, 2021
Diabetic cardiomyopathy (DCM) is a common complication associated with diabetes. The (pro)renin receptor (PRR) is an important member of the local tissue renin-angiotensin system and plays a vital role in many cardiovascular diseases.
Jie Xiong   +12 more
doaj   +1 more source

Bounded-Leakage Differential Privacy [PDF]

open access: yes, 2020
We introduce and study a relaxation of differential privacy [Dwork et al., 2006] that accounts for mechanisms that leak some additional, bounded information about the database.
Ligett, Katrina   +2 more
core   +1 more source

Peningkatan Kemurnian Radiokimia Iodium-125 Produksi PRR dengan Natrium Metabisulfit dan Reduktor Jones

open access: yesJurnal Kimia Valensi, 2017
Radioisotop 125iodium cukup dikenal luas manfaatnya, diantaranya adalah sebagai perunut (tracer) kit RIA/IRMA untuk deteksi in-vitro berbagai penyakit, sebagai sumber radiasi dalam brachytherapy penyakit kanker, sebagai perunut binding assay dalam ...
Maiyesni Maiyesni   +5 more
doaj   +1 more source

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