Results 1 to 10 of about 37,669 (165)

Overweight and obesity in south central Uganda: A population-based study.

open access: yesPLOS Global Public Health, 2022
Obesity is a rapidly growing global health challenge, but there are few population-level studies from non-urban settings in sub-Saharan Africa. We evaluated the prevalence of overweight (body mass index (BMI)>25 kg/m2), obesity (BMI>30 kg/m2), and ...
Adeoluwa Ayoola   +14 more
doaj   +2 more sources

Sensor Sensibility—HIV-1 and the Innate Immune Response

open access: yesCells, 2020
Innate immunity represents the human immune system’s first line of defense against a pathogenic intruder and is initiated by the recognition of conserved molecular structures known as pathogen-associated molecular patterns (PAMPs) by specialized ...
Xin Yin   +6 more
doaj   +1 more source

(Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-β1/SMAD3 PathwaySummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Activation of the (pro)renin receptor (PRR) up-regulates the expression of profibrotic genes in the kidney and heart. We aimed to investigate the role of PRR in hepatic fibrogenesis.
Yun-Cheng Hsieh   +10 more
doaj   +1 more source

(Pro)renin receptor involves in myocardial fibrosis and oxidative stress in diabetic cardiomyopathy via the PRR–YAP pathway

open access: yesScientific Reports, 2021
(Pro)renin receptor (PRR) and Yes-associated protein (YAP) play an important role in cardiovascular diseases. However, the role of PRR–YAP pathway in the pathogenesis of DCM is also not clear. We hypothesized that PRR–YAP pathway may promote pathological
Shiran Yu   +7 more
doaj   +1 more source

Peningkatan Kemurnian Radiokimia Iodium-125 Produksi PRR dengan Natrium Metabisulfit dan Reduktor Jones

open access: yesJurnal Kimia Valensi, 2017
Radioisotop 125iodium cukup dikenal luas manfaatnya, diantaranya adalah sebagai perunut (tracer) kit RIA/IRMA untuk deteksi in-vitro berbagai penyakit, sebagai sumber radiasi dalam brachytherapy penyakit kanker, sebagai perunut binding assay dalam ...
Maiyesni Maiyesni   +5 more
doaj   +1 more source

Effects of (Pro)renin Receptor on Diabetic Cardiomyopathy Pathological Processes in Rats via the PRR-AMPK-YAP Pathway

open access: yesFrontiers in Physiology, 2021
Diabetic cardiomyopathy (DCM) is a common complication associated with diabetes. The (pro)renin receptor (PRR) is an important member of the local tissue renin-angiotensin system and plays a vital role in many cardiovascular diseases.
Jie Xiong   +12 more
doaj   +1 more source

Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats

open access: yesFrontiers in Pharmacology, 2022
Cholestasis is the most destructive pathological manifestation of liver disease and available treatments are very limited. Paeoniae Radix Rubra (PRR) is an important traditional Chinese drug used to treat cholestasis.
Jing-Jing Xu   +9 more
doaj   +1 more source

Chitosan as a MAMP, searching for a PRR [PDF]

open access: yesPlant Signaling & Behavior, 2009
Chitosan, a deacetylated chitin derivative, behaves like a general elicitor, inducing a non-host resistance and priming a systemic acquired immunity. The defence responses elicited by chitosan include rising of cytosolic H(+) and Ca(2+), activation of MAP-kinases, callose apposition, oxidative burst, hypersensitive response (HR), synthesis of abscissic
M. Iriti, F. Faoro
openaire   +2 more sources

Agonists of Receptors of the Innate Immunity and Defective Viral Particles as New Generation of Adjuvants

open access: yesЭпидемиология и вакцинопрофилактика, 2018
Vaccines for many years act as one of the most effective and successfully used medicines. Vaccines obtained by traditional methods contain in their composition live, weakened or killed microorganisms (bacteria, viruses, etc.).
O. A. Svitich   +5 more
doaj   +1 more source

Paediatric outpatient prescriptions in France between 2010 and 2019: A nationwide population-based study

open access: yesThe Lancet Regional Health. Europe, 2021
Background: Paediatric outpatient prescription (POP) monitoring is pivotal to identify inadequate prescriptions and optimize drug use. We aimed at describing recent trends in POPs in France.
Marion Taine   +5 more
doaj   +1 more source

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