Results 91 to 100 of about 50,328 (300)

COPD disease severity and innate immune response to pathogen-associated molecular patterns

open access: yesInternational Journal of COPD, 2016
Vincent S Fan,1,2 Sina A Gharib,2,3 Thomas R Martin,1,2 Mark M Wurfel2 1VA Puget Sound Health Care System, Seattle, WA, USA; 2Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Washington, Seattle WA, USA ...
Fan VS, Gharib SA, Martin TR, Wurfel MM
doaj  

Biofilm-associated molecular patterns: BAMPs

open access: yesInfection and Immunity
Chronic infections involving bacterial biofilms are a major clinical challenge due to the ability of biofilm to resist antimicrobial treatments and host immune responses.
Peter Østrup Jensen   +2 more
doaj   +1 more source

HIV provides ample PAMPs for innate immune sensing [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Viral genomes comprise either RNA or DNA, and sometimes both, as can happen with retroviruses at different stages of their life cycle. Viral nucleic acids are pathogen-associated molecular patterns (PAMPs) that are detected by a variety of pathogen-recognition receptors (PPRs), key components of the innate immune system.
openaire   +2 more sources

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Amino Acid Sequence of Bacterial Microbe-Associated Molecular Pattern flg22 Is Required for Virulence

open access: yesMolecular Plant-Microbe Interactions, 2008
Flagellin proteins derived from Pseudomonas syringae pv. tabaci 6605 and flg22Pa (QRLSTGSRINSAKDDAAGLQIA), one of the microbe-associated molecular patterns (MAMP) in bacterial flagellin, induce cell death and growth inhibition in Arabidopsis thaliana. To
Kana Naito   +6 more
doaj   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

Electronic jelly: Engineering the mechanics of hydrogels for flexible electronics

open access: yesFlexMat, EarlyView.
By unifying mechanical reinforcement strategies—double networks, structural ordering, and dynamic interactions—this review demonstrates how engineered hydrogels can transcend their fragility to achieve the strength, toughness, and reliability required for flexible electronics, including wearable sensors, energy devices, and soft robotic systems ...
Tianfu Zheng   +2 more
wiley   +1 more source

Advanced flexible brain computer interface materials: From development to application

open access: yesFlexMat, EarlyView.
This review explores how novel materials coatings are advancing brain‐computer interface (BCI) technology. It describes how these materials help overcome key challenges in signal accuracy, biocompatibility, and device durability. The paper highlights BCI applications in medicine and entertainment, and discusses future trends that could transform human ...
Renquan Guan   +5 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

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