Results 121 to 130 of about 52,994 (295)

Chronic mycoplasma infection inhibits THP-1 cells response to PAMPs.

open access: yes, 2013
THP-1 cells, mycoplasma negative (−), positive (+) or treated with Plasmocin and confirmed to be a mycoplasma negative (P) were stimulated either with E. coli LPS or F. novicida (F.n.) for 15 hours in antibiotic-free media.
Jaykumar Grandhi (365999)   +3 more
core   +1 more source

Polymer-modified nano-Al2O3 for efficient levofloxacin removal: Mechanisms and environmental implications

open access: yesMaterials & Design
Removal of emerging antibiotic is of great importance because antibiotic resistance is serious problem for human health. Novel adsorbents are atttracted intense study but very few study has been investigated the performance of different phase structures ...
Thi Tra My Tran   +6 more
doaj   +1 more source

On PAMPs and DAMPs

open access: yesJournal of Innate Immunity, 2016
Heiko Herwald, Arne Egesten
openaire   +2 more sources

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

Functional characterizations of RIG-I to GCRV and viral/bacterial PAMPs in grass carp Ctenopharyngodon idella.

open access: yes, 2012
BackgroundRIG-I (retinoic acid inducible gene-I) is one of the key cytosolic pattern recognition receptors (PRRs) for detecting nucleotide pathogen associated molecular patterns (PAMPs) and mediating the induction of type I interferon and inflammatory ...
Limin Peng   +5 more
core   +1 more source

Complementarity in alliances: How strategic compatibility and hierarchy promote efficient cooperation in international security

open access: yesAmerican Journal of Political Science, EarlyView.
Abstract How can defense alliances reap the efficiency gains of working together when coordination and opportunism costs are high? Although specializing as part of a collective comes with economic and functional benefits, states must bargain over the distribution of those gains and ensure the costs of collective action are minimized.
J. Andrés Gannon
wiley   +1 more source

PAMPs enhance CXCR4 expression on DCs and susceptibility to productive infection with X4 virus.

open access: yes, 2013
(A) iDCs were left untreated or treated for 24 hours with the listed PAMPs. Next, DCs were washed and pretreated, or not, with EFV for 15 minutes, and then exposed to NL4-3 for another 24 hours. Cell-free supernatants were harvested at 3, 6, 9, 12 and 15
Sandra C. Côté (429133)   +3 more
core   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

open access: yesCancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo   +6 more
wiley   +1 more source

Splicing Factor Mutations in Clonal Hematopoiesis and Progression to Myeloid Neoplasms

open access: yesCancer Science, EarlyView.
Splicing factor (SF)‐mutant CH is characterized by relatively late emergence and accelerated clonal expansion in older individuals. This review summarizes its clonal dynamics, disease‐associated consequences of SF mutations in myeloid neoplasms, and candidate mechanisms that may contribute to age‐dependent selection.
Yang Lyu, Yutong Zhang, Ayana Kon
wiley   +1 more source

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