Results 111 to 120 of about 3,191,959 (309)
Pan-cancer analysis of telomere maintenance mechanisms
Journal of Biological ChemistryTelomeres, protective caps at chromosome ends, maintain genomic stability and control cell lifespan. Dysregulated telomere maintenance mechanisms (TMMs) are cancer hallmarks, enabling unchecked cell proliferation. We conducted a pan-cancer evaluation of TMM using RNA sequencing data from The Cancer Genome Atlas for 33 different cancer types and ...Meline Hakobyan, Hans Binder, Arsen Arakelyan +2 moreopenaire +2 more sourcesImmunohistochemistry and next-generation sequencing for NTRK fusion detection in differentiated thyroid cancer of children, adolescents and young adults
Brazilian Journal of OncologyIntroduction: Pan-TRK immunohistochemistry staining can assess the protein expression from NTRK gene fusions. A little is known about its utility in differentiated thyroid cancer samples from children, adolescents, and young adults patients.Ana Clara Oliveira Tosta Telles, Gabriel Jeferson Rodríguez Machado, Juliana Lima von-Ammon, Rafael Reis Campos da-Matta, Taíse Lima Cerqueira de-Oliveira, Fabyan Esberard de Lima Beltrão, Alexandre Rolim da-Paz, Fabio Hecht, Guilherme de Castro Lopes, Leonardo Freitas Boaventura Rios, Bruno da Silva Lisboa, Helton Estrela Ramos +11 moredoaj +1 more sourceResource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
, 2014 BackgroundIt is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening ...Evans, William K., Bhatia, Rick, Soghrati, Kamyar, Johnston, Michael R., Roberts, Heidi, McWilliams, Annette, English, John C, Hwang, David M, Hwang, David M., Urbanski, Stefan, Evans, William K, Goss, Glenwood D., Tsao, Ming-Sound, Sin, Don D, Johnston, Michael R, Peacock, Stuart J., Amjadi, Kayvan, Tammemagi, Martin C., Shepherd, Frances A., Xu, Zhaolin, Nicholas, Garth, Tremblay, Alain, Regier, Dean A, Sekhon, Harmanjatinder S., Sin, Don D., Liu, Geoffrey, Peacock, Stuart J, Couture, Christian, Tan, Wan C, Finley, Richard J, Cromwell, Ian, Mayo, John R., Burrowes, Paul, English, John C., Tammemagi, Martin C, Puksa, Serge, MacEachern, Paul, Goss, Glenwood D, Cressman, Sonya, Ionescu, Diana N, Shepherd, Frances A, Lam, Stephen, Leighl, Natasha B, Bolbocean, Corneliu, Finley, Richard J., Tan, Wan C., Mayo, John R, Seely, Jean M., Martel, Simon, Leighl, Natasha B., Manos, Daria, Yee, John, Sekhon, Harmanjatinder S, Atkar-Khattra, Sukhinder, Ionescu, Diana N., Regier, Dean A., Goffin, John, Seely, Jean M, Yasufuku, Kazuhiro, Cutz, Jean-Claude +59 morecore +1 more sourceA Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium
Advanced Healthcare Materials, EarlyView.Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy +8 morewiley +1 more sourcePan-cancer proteogenomics characterization of tumor immunity
CellDespite the successes of immunotherapy in cancer treatment over recent decades, less than Francesca Petralia, Weiping Ma, Tomer M. Yaron, Francesca Pia Caruso, Nicole Tignor, Joshua M. Wang, Daniel Charytonowicz, Jared L. Johnson, Emily M. Huntsman, Giacomo B. Marino, Anna Calinawan, John Erol Evangelista, Myvizhi Esai Selvan, Shrabanti Chowdhury, Dmitry Rykunov, Azra Krek, Xiaoyu Song, Berk Turhan, Karen E. Christianson, David A. Lewis, Eden Z. Deng, Daniel J.B. Clarke, Jeffrey R. Whiteaker, Jacob J. Kennedy, Lei Zhao, Rossana Lazcano Segura, Harsh Batra, Maria Gabriela Raso, Edwin Roger Parra, Rama Soundararajan, Ximing Tang, Yize Li, Xinpei Yi, Shankha Satpathy, Ying Wang, Maciej Wiznerowicz, Tania J. González-Robles, Antonio Iavarone, Sara J.C. Gosline, Boris Reva, Ana I. Robles, Alexey I. Nesvizhskii, D.R. Mani, Michael A. Gillette, Robert J. Klein, Marcin Cieslik, Bing Zhang, Amanda G. Paulovich, Robert Sebra, Zeynep H. Gümüş, Galen Hostetter, David Fenyö, Gilbert S. Omenn, Lewis C. Cantley, Avi Ma'ayan, Alexander J. Lazar, Michele Ceccarelli, Pei Wang, Jennifer Abelin, François Aguet, Yo Akiyama, Eunkyung An, Shankara Anand, Meenakshi Anurag, Özgün Babur, Jasmin Bavarva, Chet Birger, Michael J. Birrer, Song Cao, Steven A. Carr, Daniel W. Chan, Arul M. Chinnaiyan, Hanbyul Cho, Karl Clauser, Antonio Colaprico, Daniel Cui Zhou, Felipe da Veiga Leprevost, Corbin Day, Saravana M. Dhanasekaran, Li Ding, Marcin J. Domagalski, Yongchao Dou, Brian J. Druker, Nathan Edwards, Matthew J. Ellis, Steven M. Foltz, Alicia Francis, Yifat Geffen, Gad Getz, David I. Heiman, Runyu Hong, Yingwei Hu, Chen Huang, Eric J. Jaehnig, Scott D. Jewell, Jiayi Ji, Wen Jiang, Lizabeth Katsnelson, Karen A. Ketchum, Iga Kolodziejczak, Karsten Krug, Chandan Kumar-Sinha, Jonathan T. Lei, Wen-Wei Liang, Yuxing Liao, Caleb M. Lindgren, Tao Liu, Wenke Liu, Jason McDermott, Wilson McKerrow, Mehdi Mesri, Michael Brodie Mumphrey, Chelsea J. Newton, Robert Oldroyd, Samuel H. Payne, Pietro Pugliese, Karin D. Rodland, Fernanda Martins Rodrigues, Kelly V. Ruggles, Sara R. Savage, Eric E. Schadt, Michael Schnaubelt, Tobias Schraink, Stephan Schürer, Zhiao Shi, Richard D. Smith, Feng Song, Yizhe Song, Vasileios Stathias, Erik P. Storrs, Jimin Tan, Nadezhda V. Terekhanova, Ratna R. Thangudu, Mathangi Thiagarajan, Liang-Bo Wang, Bo Wen, Yige Wu, Matthew A. Wyczalkowski, Lijun Yao, Qing Kay Li, Hui Zhang, Qing Zhang, Xu Zhang, Zhen Zhang +143 moreopenaire +2 more sourcesThe 5-Hydroxymethylcytosine Landscape of Prostate Cancer.
UNLABELLED: Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers.Sjöström, M, Ning, Y, Witte, ON, Boutros, PC, Huang, FW, Perry, MD, Gleave, M, Zwart, W, Shrestha, R, Phillips, T, Maher, CA, He, HH, Aggarwal, R, Fraser, M, Petricca, J, Small, EJ, Quigley, DA, Bjartell, A, Ye, W, Morgans, AK, Ashworth, A, Maurice-Dror, C, Ng, SWS, Moreno-Rodriguez, T, Haffner, MC, Levy, S, Beer, TM, Gilbert, LA, Zhao, SG, Fong, L, Rettig, MB, Annala, M, Bose, R, He, C, Lloyd, P, Mahajan, NP, Cui, X-L, McCarthy, E, Chou, J, Hua, JT, Evans, CP, Feng, FY, Li, H, Chen, S, Chen, WS, Foye, A, Zoubeidi, A, Chi, KN, Lang, JM, Bergamaschi, A, Chesner, L, Tran, PT, Lundberg, A, Herberts, C, Posadas, EM, Wyatt, AW, Luo, J, Maheshwari, A, Zhang, M, Thomas, GV, Huang, J, Reiter, RE, Alumkal, JJ, Lara, PN +63 morecore +1 more sourceMagnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications
Advanced Materials Technologies, EarlyView.Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...Li Ke, Moses Kumi, Xiaoming Tao, Junhong Pu +3 morewiley +1 more sourcePrognostic value of TMTC1 in pan-cancer analysis
HeliyonTransmembrane and tetratricopeptide repeat containing 1 (TMTC1) is a recently discovered enzyme involved in the O-mannosylation of cadherins and protocadherins. It has been implicated in various types of cancer, but the overall prognostic significance of TMTC1 in pan-cancer and its potential as an immunotherapeutic target remain unclear.We applied ...Ying Zhang, Dan Wu, Tiantian Yu, Yao Liu, Chunbo Zhao, Ruihong Xue +5 moreopenaire +3 more sources
