Results 161 to 170 of about 3,942,953 (265)

Pan-cancer multi-omics analysis of pharmacogenomic alterations. [PDF]

Front Bioinform
AlMulla A, Kaur S, Balyan P, Al-Saafin S, Balyan MK, Velayutham D, Jithesh PV.   +6 more
europepmc   +1 more source

The Journal of Obstetrics and Gynaecology – a new era

Journal of Obstetrics and Gynaecology, 2023
Ayman A. A. Ewies
doaj   +1 more source

Cancer in Ireland 1994-2017 with estimates for 2017-2019: annual report of the National Cancer Registry

, 2019
This year’s report estimates that numbers of invasive cancers (excluding non-melanoma skin cancer) have risen to about 23,890 cases diagnosed annually during 2017-2019 (12,770 males and 11,120 females), or 35,441 cases including all invasive cancers.
National Cancer Registry Ireland (NCRI)
core  

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

A Pan-Cancer Analysis of microRNA Tissue Specificity and Its Association with Dysregulation. [PDF]

Int J Mol Sci
Ismailov A, Belogurov A, Evpak A, Poptsova M.   +3 more
europepmc   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

RPLP0 identified as a ferroptosis regulator in HCC through pan-cancer analysis. [PDF]

Front Oncol
Wang Z, Chen S, Yan B, Peng X, Chen L, Su M, Li H.   +6 more
europepmc   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Enhancing pan-cancer spatial transcriptomics at single-cell resolution with stPainter. [PDF]

Nat Commun
Yang Y, Luo Y, Zhang K, Zhang Z, Peng H, Cao C, Liu Q, Ma B, Chen Y, Shen L, Chen E.   +10 more
europepmc   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source