Results 101 to 110 of about 1,691,339 (303)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The goat pan-genome reveals patterns of gene loss during domestication

Journal of Animal Science and Biotechnology
Background Unveiling genetic diversity features and understanding the genetic mechanisms of diverse goat phenotypes are pivotal in facilitating the preservation and utilization of these genetic resources.
Jiaxin Liu, Yilong Shi, Dongxin Mo, Lingyun Luo, Songsong Xu, Fenghua Lv   +5 more
doaj   +1 more source

Application of Comparative Genomics for the Development of PCR Primers for the Detection of Harmful or Beneficial Microorganisms in Food: Mini-Review

Foods
Gene markers are widely utilized for detecting harmful and beneficial microorganisms in food products. Primer sequences targeting the 16S rRNA region, recognized as a conserved region, have been conventionally employed in PCR analyses.
Sang-Soon Kim
doaj   +1 more source

Genomic fluidity: an integrative view of gene diversity within microbial populations

BMC Genomics, 2011
Background The dual concepts of pan and core genomes have been widely adopted as means to assess the distribution of gene families within microbial species and genera.
Bergman Nicholas H, Haegeman Bart, Kislyuk Andrey O, Weitz Joshua S   +3 more
doaj   +1 more source

Additional file 11 of PangenomeNet: a pan-genome-based network reveals functional modules on antimicrobial resistome for Escherichia coli strains

, 2021
Additional file 11: File S10.
Hsuan-Lin Her (11678727), Po-Ting Lin (11678730), Yu-Wei Wu (16196)   +2 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Pan-genome prediction.

, 2013
The number of pan-genome OGs (blue) and core genome OGs (red) is shown as a function of genomes added to the pan-genome. OGs present in only one annotated genome were not included if they appeared to represent gene fragments or overpredicted small genes.
Johan E. T. van Hylckama Vlieg (435339), Sylvain Brisse (87594), Jos Boekhorst (81341), Michiel Wels (16311), Justyna Polka (435337), Roland J. Siezen (12053), Christian Chervaux (435338), Tamara Smokvina (435336)   +7 more
core   +2 more sources

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Genomic analysis of three African strains of Bacillus anthracis demonstrates that they are part of the clonal expansion of an exclusively pathogenic bacterium

New Microbes and New Infections, 2014
Bacillus anthracis is the causative agent of anthrax and is classified as a ‘Category A’ biological weapon. Six complete genomes of B. anthracis (A0248, Ames, Ames Ancestor, CDC684, H0491, and Sterne) are currently available. In this report, we add three
L. Rouli, M. Mbengue, C. Robert, M. Ndiaye, B. La Scola, D. Raoult   +5 more
doaj   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source