Results 201 to 210 of about 1,691,339 (303)

Pan-Genome Analysis and Expression Profiling of <i>HIPP</i> Gene Family in Cassava. [PDF]

Genes (Basel)
Xia Z, Zhao J, Wang C, Wu S, Zang Y, Wang D, Zhu S, Min Y.   +7 more
europepmc   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Analysis of the Vibrionaceae pan-genome

, 2013
In the presented work the bacterial family Vibrionaceae was used as a model to investigate bacterial diversity on a gene level and to analyze the underlying concepts of bacterial niche adaptation and evolution. For this, the genomes of a diverse dataset of 64 Vibrionaceae isolates from various environments and temperature zones were analyzed using ...
openaire   +1 more source

Pan-genome analysis and abiotic stress expression of the <i>SWEET</i> gene family in <i>Brassica napus</i>. [PDF]

Front Plant Sci
Xu J, Chen J, Long J, Xue T, Zhang X.
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Genomic characterization of clinical Helicobacter pylori strains from Korea: insights into phylogeny, pan-genome structure, and virulence factors. [PDF]

BMC Microbiol
Jung HE, Bang CS, Ahn JY, Jung HY, Lee SM, Kim SW, Chae DW, Gong EJ.   +7 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Pan-genome and antibiotic resistance insights into Xanthomonas citri pv. punicae pathotypes. [PDF]

BMC Microbiol
Rathna V, Kukreti A, Prasannakumar MK, C M, R K, Patil SS, Venkateshbabu G, Devanna P, J H, Banakar SN, Sarangi AN, Vaidya K, Rymbai S, Mahesh HB, Soolanayakanahally RY, Kagale S.   +15 more
europepmc   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Mistranslation from an endogenous tRNA variant in human pan-genome cell lines. [PDF]

Nucleic Acids Res
Rozik P, Moore H, Lant JT, Hoffman KS, Schultz SK, Afzal B, Chan PP, Flynn LE, Heinemann IU, Lowe TM, O'Donoghue P.   +10 more
europepmc   +1 more source