Results 211 to 220 of about 174,716 (299)

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +2 more sources

Pan-Genome-Based Characterization of the PYL Transcription Factor Family in <i>Populus</i>. [PDF]

Plants (Basel)
Han X, Qiu C, Gai Z, Zhai J, Song J, Sun J, Li Z.   +6 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Pan-genome analysis reveals the evolution and diversity of Malus. [PDF]

Nat Genet
Li W, Chu C, Zhang T, Sun H, Wang S, Liu Z, Wang Z, Li H, Li Y, Zhang X, Geng Z, Wang Y, Li Y, Zhang H, Fan W, Wang Y, Xu X, Cheng L, Zhang D, Xiong Y, Li H, Zhou B, Guan Q, Deng CH, Han Y, Ma H, Han Z.   +26 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Integrating pan-genome analysis, GWAS, and interpretable machine learning to prioritize trait-associated structural variations in Setaria italica. [PDF]

Plant Commun
Wang W, Wu T, Fan G, Zhang S, Liu S, Jiang S, Cheng Q, Shang M, Xu Y, Zhang W, Zhang J, Wang X, Zhao Z, Yan J.   +13 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Pan-Genome Analysis of <i>Cannabis sativa</i>: Insights on Genomic Diversity, Evolution, and Environment Adaption. [PDF]

Int J Mol Sci
Wang S, Zhong X, Cheng Y, Yu Y, Wan J, Liu Q, Shu Y, Wu X, Li Y.   +8 more
europepmc   +1 more source

Pan-genome assembly of vine tea (<i>Nekemias grossedentata</i>) reveals structural variation in its dihydromyricetin biosynthesis diversity. [PDF]

Hortic Res
Han D, Na S, Hou Z, Li F, Zhu C, Li Y, Zheng Y, Mo Q, Chen J, Xia S, Zhou X, Yang C, Liu J.   +12 more
europepmc   +1 more source