Results 231 to 240 of about 176,950 (261)
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2018
The pan-genome of a species is comprised of genes/sequences that are present in all individuals in the species (core genome) and genes/sequences that are present in only a subset of individuals within the species (dispensable genome). In maize, the study of the pan-genome began in the 1940s through cytogenetic experiments and has seen an increased ...
Alex B. Brohammer +2 more
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The pan-genome of a species is comprised of genes/sequences that are present in all individuals in the species (core genome) and genes/sequences that are present in only a subset of individuals within the species (dispensable genome). In maize, the study of the pan-genome began in the 1940s through cytogenetic experiments and has seen an increased ...
Alex B. Brohammer +2 more
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Transposable elements and the plant pan-genomes
Current Opinion in Plant Biology, 2007The comparative sequencing of several grass genomes has revealed that transposable elements are largely responsible for extensive variation in both intergenic and local genic content, not only between closely related species but also among individuals within a species.
MORGANTE, Michele +2 more
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Orthopoxvirus pan-genomic DNA assay
Journal of Virological Methods, 2007A genome-spanning assay is described that enables laboratory confirmation of infections with orthopoxviruses (OPVs), particularly Vaccinia, Monkeypox, and Variola viruses, which can cause vesiculo-pustular rash illnesses in humans. The assay uses a series of polymerase chain reaction (PCR) amplicons that overlap to span the approximately 200kilobase ...
Yu, Li +4 more
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2019
Due to their tendency to have a high recombination rate, bacterial genomes are highly diverse across different strains. This diversity may even be in the form of the presence or absence of entire genes; therefore, each strain might have its own combination of genes. The pan-genome represents the complete gene pool of a species.
Arash Iranzadeh, Nicola Jane Mulder
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Due to their tendency to have a high recombination rate, bacterial genomes are highly diverse across different strains. This diversity may even be in the form of the presence or absence of entire genes; therefore, each strain might have its own combination of genes. The pan-genome represents the complete gene pool of a species.
Arash Iranzadeh, Nicola Jane Mulder
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Estimating the size of the bacterial pan-genome
Trends in Genetics, 2009The 'pan-genome' denotes the set of all genes present in the genomes of a group of organisms. Here, we extend the pan-genome concept to higher taxonomic units. Using 573 sequenced genomes, we estimate the size of the bacterial pan-genome based on the frequency of occurrences of genes among sampled genomes. Using gene- and genome-centered approaches, we
Pascal, Lapierre, J Peter, Gogarten
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Comparative genomics: the bacterial pan-genome
Current Opinion in Microbiology, 2008Bacterial genome sequencing has become so easy and accessible that the genomes of multiple strains of more and more individual species have been and will be generated. These data sets provide for in depth analysis of intra-species diversity from various aspects.
Hervé, Tettelin +3 more
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Ten years of pan-genome analyses
Current Opinion in Microbiology, 2015Next generation sequencing technologies have engendered a genome sequence data deluge in public databases. Genome analyses have transitioned from single or few genomes to hundreds to thousands of genomes. Pan-genome analyses provide a framework for estimating the genomic diversity of the dataset at hand and predicting the number of additional whole ...
George, Vernikos +3 more
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Pan-Genome of Brucella Species
Indian Journal of Microbiology, 2014Whole-genome sequencing of bacterial pathogens has high impact on diagnosis and development of prophylaxis to human and veterinary disease. To study the genetic variations and relatedness among Brucella spp., we have examined the pan-genomic content of 18 Brucella complete genomes from NCBI using GView and Panseq server.
Jagadesan Sankarasubramanian +4 more
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Journal of Clinical Oncology, 2019
3099 Background: FGFR2 genomic alterations (GA) have been described in a variety of solid tumors and emerged as biomarkers for investigational agents undergoing clinical trials. Methods: 201,766 primarily relapsed/refractory malignancies were evaluated with a hybrid-capture based sequencing assay Tumor mutational burden (TMB) was determined on 0.8-1 ...
Russell Madison +19 more
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3099 Background: FGFR2 genomic alterations (GA) have been described in a variety of solid tumors and emerged as biomarkers for investigational agents undergoing clinical trials. Methods: 201,766 primarily relapsed/refractory malignancies were evaluated with a hybrid-capture based sequencing assay Tumor mutational burden (TMB) was determined on 0.8-1 ...
Russell Madison +19 more
openaire +1 more source