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Ethical and legal studies relating to the program to map and sequence the human genome.
National Institute of General Medical Sciences (United States). Office of Human Genome Research.
core
Deciphering the near-complete genome and conducting pan-genome analysis of <i>Brassica oleracea</i>. [PDF]
Li Q +11 more
europepmc +1 more source
Pan-Genome miRNomics in Brachypodium [PDF]
Pan-genomes are efficient tools for the identification of conserved and varying genomic sequences within lineages of a species. Investigating genetic variations might lead to the discovery of genes present in a subset of lineages, which might contribute into beneficial agronomic traits such as stress resistance or yield.
Sezgi Kaya, Hikmet Budak, Meral Yüce
exaly +5 more sources
Pan-Genome of Wild and Cultivated Soybeans [PDF]
Soybean is one of the most important vegetable oil and protein feed crops. To capture the entire genomic diversity, it is needed to construct a complete high-quality pan-genome from diverse soybean accessions. In this study, we performed individual de novo genome assemblies for 26 representative soybeans that were selected from 2,898 deeply sequenced ...
Zhixi Tian, Bin Han, Chengzhi Liang
exaly +3 more sources
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The Barley and Wheat Pan-Genomes
2022To unlock the genetic potential in crops, multi-genome comparisons are an essential tool. Decreasing costs and improved sequencing technologies have democratized plant genome sequencing and led to a vast increase in the amount of available reference sequences on the one hand and enabled the assembly of even the largest and most complex and repetitive ...
Kamal, N. +7 more
openaire +3 more sources
Pan-genomics in the human genome era
Since the early days of the genome era, the scientific community has relied on a single 'reference' genome for each species, which is used as the basis for a wide range of genetic analyses, including studies of variation within and across species. As sequencing costs have dropped, thousands of new genomes have been sequenced, and scientists have come ...
Steven L Salzberg +2 more
exaly +4 more sources
Current Opinion in Genetics & Development, 2005
A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed. Experimental data have shown that in some species new genes are discovered even after sequencing the genomes of several strains.
Duccio, Medini +4 more
openaire +2 more sources
A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed. Experimental data have shown that in some species new genes are discovered even after sequencing the genomes of several strains.
Duccio, Medini +4 more
openaire +2 more sources
Plant pan-genomics and its applications
Molecular Plant, 2023Plant genomes are so highly diverse that a substantial proportion of genomic sequences are not shared among individuals. The variable DNA sequences, along with the conserved core sequences, compose the more sophisticated pan-genome that represents the collection of all non-redundant DNA in a species.
Junpeng, Shi +3 more
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The Core and Pan-Genome of the Vibrionaceae
2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing, 2009Species of the family Vibrionaceae are ubiquitous in marine environments and the family contains numerous important pathogens of humans and marine species. In order to find the core, accessory and pan-proteome of this family, we deduced the complete set of orthologs for eleven strains from this family.
Timothy G. Lilburn +2 more
openaire +1 more source
Plant Pan-Genomics Comes of Age
Annual Review of Plant Biology, 2021A pan-genome is the nonredundant collection of genes and/or DNA sequences in a species. Numerous studies have shown that plant pan-genomes are typically much larger than the genome of any individual and that a sizable fraction of the genes in any individual are present in only some genomes.
Li, Lei +5 more
openaire +2 more sources

