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Pan-Genome of Brucella Species

Indian Journal of Microbiology, 2014
Whole-genome sequencing of bacterial pathogens has high impact on diagnosis and development of prophylaxis to human and veterinary disease. To study the genetic variations and relatedness among Brucella spp., we have examined the pan-genomic content of 18 Brucella complete genomes from NCBI using GView and Panseq server.
Jagadesan Sankarasubramanian   +4 more
openaire   +1 more source

FGFR2: A pan-genomic target.

Journal of Clinical Oncology, 2019
3099 Background: FGFR2 genomic alterations (GA) have been described in a variety of solid tumors and emerged as biomarkers for investigational agents undergoing clinical trials. Methods: 201,766 primarily relapsed/refractory malignancies were evaluated with a hybrid-capture based sequencing assay Tumor mutational burden (TMB) was determined on 0.8-1 ...
Russell Madison   +19 more
openaire   +1 more source

Pan-Genomics

2021
Maryam Javed   +2 more
openaire   +1 more source

The Bacterial Pan-Genome and Reverse Vaccinology

2009
The whole genome sequence of most human bacterial pathogens is available and the advent of next-generation sequencing technologies will result in a large number of sequenced isolates per pathogenic species. The study of multiple genome sequences of a given bacterium provides insights into its evolution, pathogenic potential and diversity.
openaire   +2 more sources

Sequencing the species pan-genome

Nature Reviews Microbiology, 2009
This month's Genome Watch discusses the recent advances in sequencing technology that have allowed microbiologists to determine the genome sequences not just of individual species but also of entire genera and have allowed a view of the entire pan-bacterial genome.
openaire   +1 more source

The Danish reference pan genome

2014
Sequencing of Danish parent-offspring trios to determine genomic variation within the Danish population. First release comprises of ten trios sequenced to 50X using libraries of insert sizes from 180nt to 800nt.
openaire   +1 more source

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