Results 201 to 210 of about 714,927 (305)

The Wandering Pancreas: A Rare Case of Complex Hiatal Hernia Presenting With Thoracic Symptoms. [PDF]

Cureus
El Hassani A, Abbay H, Slioui B, Mouhsine A, Bellasri S.   +4 more
europepmc   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

Diameter of the fetal pancreas and abdomen-to-pancreas-ratio: novel ultrasound parameters in fetal growth restriction. [PDF]

Arch Gynecol Obstet
von der Gathen L, Braun J, Möllers M, De Santis C, Willy D, Schmidt R, Oberste K, Schmitz R, Oelmeier K.   +8 more
europepmc   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

Utility of breath-hold half-Fourier single-shot turbo spin-echo with deep learning-based reconstruction for acquiring fat-suppressed T2-weighted images of the pancreas. [PDF]

Eur J Radiol Open
Nonaka T, Ichinohe F, Oyama K, Yamada A, Hayashihara H, Adachi Y, Kito Y, Kanki Y, Maruyama K, Nickel MD, Fujinaga Y.   +10 more
europepmc   +1 more source

ANNULAR PANCREAS

Annals of Surgery, 1952
openaire   +3 more sources

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Editorial Expression of Concern to: The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer

Cell Death and Disease
Wan-Li Ge, Qun Chen, Ling-Dong Meng, Xu-Min Huang, Guo-dong Shi, Qing-Qing Zong, Peng Shen, Yi-Chao Lu, Yi-Han Zhang, Yi Miao, Jing-Jing Zhang, Kui-Rong Jiang   +11 more
doaj   +1 more source

Editorial: m6A methylation and cancer immunity

Frontiers in Immunology
Qun Chen, Qun Chen, Hao Yuan, Hao Yuan, Peng-Fei Wu, Peng-Fei Wu   +5 more
doaj   +1 more source

Pancreatic Choristoma of the Spleen, a Rare Incidental Finding: A Case Report. [PDF]

Int Med Case Rep J
Alokozay E, Marofi M, Sarwary MF, Sediqi M, Bawarzai A, Kamal MI, Modabber MH, Tariq W.   +7 more
europepmc   +1 more source