Results 221 to 230 of about 534,909 (297)

Editorial: Organ transplantation by 2040

Frontiers in Transplantation
Jerzy W. Kupiec-Weglinski, Ronald W. Busuttil   +1 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Dueling with the dual artery blood supply in pancreas transplantation: why replace the Y? [PDF]

Gland Surg
Fridell JA, Stratta RJ.
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Evolving Trends in the Management of Duodenal Leaks After Pancreas Transplantation: A Single-Centre Experience. [PDF]

Transpl Int
Ray S, Hobeika C, Norgate A, Sawicka Z, Schiff J, Sapisochin G, McGilvray ID, Selzner M, Reichman TW, Shwaartz C.   +9 more
europepmc   +1 more source

Does Everyone Need CEA? A Case for Selective Omission After Colorectal Cancer Resection

ANZ Journal of Surgery, EarlyView.
Matthew P. Irwin, Muhammad F. Rosley, Samuel Dickson, Gregory J. Nolan   +3 more
wiley   +1 more source

Indole‐3‐Propionic Acid Drives Dendritic H3K27 Acetylation to Enhance CD8+ T Cell Immunity in Hepatocellular Carcinoma

Cancer Science, EarlyView.
The gut microbiota metabolite indole ‐ 3 ‐ propionic acid（IPA) enhanced the inhibitory effect of SCB on tumor growth in HCC mice. IPA upregulated IL‐12A expression through facilitating acetylation of H3K27 in DCs. IPA elevated IL‐12A expression in DCs to promote CD8+ T cell anti‐tumor immunity and ultimately enhances the efficacy of SCB therapy against
Rui Zhao, Siqi Liu, Qian Zhang, Wenrui Wang, Lanlan Yang, Xue Shao, Shengnan Jia, Zhenjing Jin   +7 more
wiley   +1 more source

Tissue Factor‐High Ovarian Clear Cell Carcinoma Shows Immune‐Cold Features and Preclinical Activity of Tisotumab Vedotin

Cancer Science, EarlyView.
F3/TF‐high ovarian clear cell carcinoma exhibits an immune‐cold phenotype characterized by reduced immune‐cell fractions and attenuated cancer‐cell interferon programs, with frequent B7‐H4 co‐expression. Patient‐derived models show preclinical sensitivity to the TF‐directed antibody–drug conjugate tisotumab vedotin.
Yutaro Mori, Ryo Tamura, Kotaro Takahashi, Kaoru Yamawaki, Tatsuya Ishiguro, Teiichi Motoyama, Koji Okamoto, Kosuke Yoshihara   +7 more
wiley   +1 more source

Belatacept in Pancreas Transplantation: Promising Insights From a Cohort Series. [PDF]

Transpl Int
Masset C, Garandeau C, Ville S, Giral M, Houzet A, Branchereau J, Chelghaf I, Mesnard B, Blancho G, Dantal J, Cantarovich D.   +10 more
europepmc   +1 more source

How to Do a Laparoscopic Left Hepatectomy for Cystic Lesions Compressing the Middle Hepatic Vein: The Hemodynamic Advantage of Pneumoperitoneum

ANZ Journal of Surgery, EarlyView.
Jonathan Ben Daniel, Krishna Kotecha, Kai Brown, Anubhav Mittal, Jaswinder Samra   +4 more
wiley   +1 more source