Results 241 to 250 of about 534,909 (297)

PPI and researcher perspectives of islet transplantation therapy for type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Islet transplantation offers the potential of a cure for type 1 diabetes (T1D), but the limited availability of human donor islets means that this therapy is currently only available to a small group of people with T1D who have intractable hypoglycaemia.
Peter M. Jones, Sarah Gatward, Lesley Beadle, Amanda Panizza, Clare Blaydon‐Ellis, Sara Caxaria, Aidan Cruddace, Christine Deal, Ranna Patel, Alexander Silverstein, Lydia F. Daniels Gatward, Tzu‐Wen Hong, Rosie Sullivan, William T. Blackstone Whines, Aileen J. F. King, Shanta J. Persaud   +15 more
wiley   +1 more source

Pancreas Transplantation Outcome Predictions-PTOP: A Risk Prediction Tool for Pancreas and Pancreas-Kidney Transplants Based on a European Cohort. [PDF]

Transplant Direct
Miller G, Ankerst DP, Kattan MW, Hüser N, Stocker F, Vogelaar S, van Bruchem M, Assfalg V.   +7 more
europepmc   +1 more source

Participant and physician perspectives on the use of SGLT2 inhibitors in type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Sodium–glucose co‐transporter inhibitors (SGLT2i) have proven cardiorenal benefits in type 2 diabetes and are promising as adjunct‐to‐insulin therapy in participants with type 1 diabetes (T1D). However, clinical use in T1D has been limited owing to a lack of regulatory approval and the augmented risk of diabetic ketoacidosis (DKA ...
Julia Fielden, Pam Leblanc, Chloe Parezanovic, Vikas S. Sridhar, Bruce A. Perkins, David Z. Cherney, David J. T. Campbell   +6 more
wiley   +1 more source

Incretin‐Based Therapies as Cardiometabolic Interventions: Outcome Hierarchy, Receptor‐Network Pharmacology and Phenotype‐Based Clinical Positioning

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek, Hajnalka Lőrincz, Mariann Harangi, Attila Csaba Nagy   +3 more
wiley   +1 more source

Antenatal Corticosteroids in Gestational Diabetes: A Systematic Review of Glycemic Response and Management Strategies

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Antenatal corticosteroids (ACS) promote foetal lung maturation in pregnancies at risk of preterm birth; however, in gestational diabetes mellitus (GDM), they can exacerbate maternal glycemia and contribute to adverse neonatal outcomes. Clinical guidelines offer limited direction on optimal treatment adjustment.
Alexandra Katz, Aidan Shulkin, Samantha Jacobson, Chella Price, Michael A. Tsoukas, Isabella Albanese, Agnieszka Majdan, Jill Pancer, Ariane Godbout, Kaberi Dasgupta, Anne‐Sophie Brazeau, Tricia Peters   +11 more
wiley   +1 more source

Donor noradrenaline use is associated with better allograft survival in recipients of pancreas transplantation. [PDF]

Ann R Coll Surg Engl
Shapey IM, Summers A, Yiannoullou P, Fullwood C, Augustine T, Rutter MK, van Dellen D.   +6 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist Use Is Associated With Improved Lung Function in Cystic Fibrosis‐Related Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Luke A. Ephraums, Edward R. Mignone, Kylie Lange, Ashlee Routley, Judith Morton, Emily Hopkins, Sally Chapman, Lucia Gagliardi, Michael Horowitz, Mahesh M. Umapathysivam   +9 more
wiley   +1 more source