Results 231 to 240 of about 534,909 (297)

Human Gallbladder Cancer Organoids

Cell Proliferation, EarlyView.
This guideline provides standardized requirements and quality control measures for human gallbladder cancer organoids, supporting their reliable application in research and precision medicine. It aims to promote methodological consistency, facilitate international collaboration, and accelerate translational research and clinical implementation.
Dongxi Xiang, Ting Gong, Yinjie Zhu, Bin Jia, Chen Zhang, Ning Tang, Weiping Wang, Yalong Wang, Laiping Zhong, Yanmei Zou, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Xiaoguang Wang, Zhan Wang, Aina He, Yonggang Wang, Zebing Liu, Jiabei Wang, Feng Xu, Ganglong Gao, Xiaonan Kang, Shuai Gong, Xianming Kong, Chunyan Dong, Aijin Ma, Gengming Niu, Guiying Wei, Hongling Zhao, Xiongxiong Lu, Jie Cao, Tongbiao Zhao, Zizhen Zhang, Yingbin Liu   +37 more
wiley   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Generating strategies for a national comeback in pancreas transplantation: A Delphi survey and US conference report. [PDF]

Am J Transplant
Parsons RF, Lentine KL, Doshi M, Dunn TB, Forbes R, Fridell JA, Jesse MT, Pavlakis M, Sawinski D, Singh N, Axelrod DA, Cooper M, Workshop Participants.   +12 more
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Liver and pancreas transplantation in adult donor and recipients with situs inversus totalis: a case series and review of the literature. [PDF]

J Med Case Rep
Shamsaeefar A, Masjedi F, Roozbeh J, Nazari SS, Zarei E, Jafari M, Farifteh S, Alikhani M, Eslamian M, Mardani M, Naseri R, Nikoupour H.   +11 more
europepmc   +1 more source

A Comprehensive Comparative Analysis of Sequence‐Based Deep Learning Models for Single‐Cell Genomics

Cell Proliferation, EarlyView.
To streamline the application of sequence‐based DL methods in single‐cell genomics, we established a two‐layer CNN as our baseline model. We focus our benchmark on how data characteristics, hyperparameter optimization, and advanced model architectures impact performance across sequence‐to‐expression and sequence‐to‐regulation tasks.
Guoxia Wen, Jiaqi Li, Hanyu Wu, Jialing Fang, Yuting Fu, Mengmeng Jiang, Yuqing Mei, Rui Xu, Yuxuan Du, Siran Chu, Guoji Guo, Xiaoping Han, Jingjing Wang   +12 more
wiley   +1 more source

Belatacept Rescue Therapy in the Early Period After Simultaneous Kidney-Pancreas Transplantation. [PDF]

Transpl Int
Esposito L, Cuellar E, Marion O, Del Bello A, Hebral AL, Sallusto F, Muscari F, Prudhomme T, Kamar N.   +8 more
europepmc   +1 more source

Eruptive Acral Melanocytic Lesions Associated With Capecitabine

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eruptive nevi and lentigines have been reported to occur in the setting of immunosuppression, which may be medication‐induced. The associated histopathologic findings have not been well described in the literature. Herein, we report the case of a woman in her 60s who had been receiving chemotherapy treatment with capecitabine, a prodrug of 5 ...
Madison Smith, Annie Jin, Jonathan A. Miles, Rosalie Elenitsas, Danielle M. DeHoratius, Emily Y. Chu   +5 more
wiley   +1 more source

Risk of cytomegalovirus infection and subsequent allograft failure after pancreas transplantation. [PDF]

Am J Transplant
Yetmar ZA, Kudva YC, Seville MT, Bosch W, Huskey JL, Jarmi T, Kukla A, Dean PG, Razonable RR, Beam E.   +9 more
europepmc   +1 more source

Evaluating EndoC βH5 pseudoislets as a model for human islet transplantation

Diabetic Medicine, EarlyView.
Abstract Aims The EndoC βH5 cell line represents a promising human β‐cell model for preclinical diabetes research. Indeed, EndoC βH5 cells aggregate into islet‐like organoids, secrete insulin in a glucose‐dependent manner, and express a variety of β‐cell functional markers.
Lydia F. Daniels Gatward, William T. Blackstone Whines, Tzu‐Wen Hong, Rosie Sullivan, Jessica Starikova, Adya Lonsane, Ryea Arora, Victoria Salem, Min Zhao, Peter M. Jones, Aileen F. J. King, Shanta J. Persaud   +11 more
wiley   +1 more source