Results 251 to 260 of about 96,616 (294)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

The contribution of transplantation to gastroenterologic knowledge [PDF]

, 1994
Starzl, TE
core  

Effect of Lactobacillus plantarum Extracellular Vesicles on Lipid Metabolism in Mice Fed a High‐Fat Diet

Molecular Nutrition &Food Research, EarlyView.
Extracellular vesicles from Lactobacillus plantarum improved lipid metabolism in HFD‐fed mice by regulating hepatic genes involved in lipid synthesis and oxidation. They also alleviated intestinal dysfunction by reducing inflammation, enhancing barrier function, and modulating gut microbiota and metabolites, underscoring their therapeutic potential in ...
Shan‐Shan Xu, Chun‐Jing Yu, Meng‐Yao Qin, Yan Zhang, Jia‐Ping Jiang, Wei Liu, Yu Pan, Song Zhang, Xiao‐Yu Zhao   +8 more
wiley   +1 more source

Liver Transplantation in the World: Present Conditions of Liver Transplantation from Cadaver Donors in USA. [PDF]

, 1995
Marino, Ignazio Roberto, Starzl, Thomas E   +1 more
core  

Dietary Blueberry Supplementation Attenuates the Effects of an Ultra‐Processed Food Cafeteria Diet on Weight Gain and Metabolic Parameters, Enhancing Nutrigenomic Profiles in C57BL/6 Mice

Molecular Nutrition &Food Research, EarlyView.
1. Experimental Design (left panel) • Icons: ∘ Three C57BL/6 mice groups ∘ Control group (Standard chow) ∘ Cafeteria diet (cookies, soda, sausage, condensed milk, chow) ∘ CAFD + Blueberry (CAFD + BB smoothie and pellets) • Group Labels: ∘ Control (C): Standard diet ∘ CAFD: Cafeteria diet + SD ∘ BB: CAFD + BB • Duration: 16 weeks • Arrow pointing to ...
Felipe Mateus Pellenz, Mayara Souza de Oliveira, Shiva Cerutti Witteé, Joana Raquel Nunes Lemos, Bianca Gomes Panis, Isadora Cristina Godoy de Lima, Celina Fagundes da Silva, Anna Carolina Meireles Vieira, Mariana Rauback Aubin, Luciane Moretto, Monique Banik Siqueira, Eliandra Girardi, Raif Gregorio Nasre‐Nasser, Karla Suzana Moresco, Letícia de Almeida Brondani, Guilherme Coutinho Kullmann Duarte, Rafael Aguiar Marschner, Bianca Marmontel de Souza, Daisy Crispim   +18 more
wiley   +1 more source

Effects of Genistein on Inflammasome Induced Pancreatic β‐Cell Apoptosis by Dexamethasone

Molecular Nutrition &Food Research, EarlyView.
The possible mechanism of genistein‐mediated protection against dexamethasone‐induced pancreatic β‐cell apoptosis. Genistein decreases the activation of IRE‐1α, resulting in the reduction of sXBP1, JNK, TXNIP, NLRP3, and IL‐1β expression. Genistein inhibits dexamethasone‐induced pancreatic β‐cell apoptosis.
Nattinee Jitprawet, Jatuporn Sujjitjoon, Petcharee Maneethorn, Namoiy Semprasert, Suwattanee Kooptiwut   +4 more
wiley   +1 more source

Intrapancreatic islet transplantation as a potential solution to chronic failure of intraportal islet grafts. [PDF]

, 1993
Carroll, PB, Demetris, AJ, Fontes, PA, Ildstad, ST, Nussler, AK, Ricordi, C, Rilo, HL, Starzl, TE, Tzakis, AG   +8 more
core  

The use of octreotide in pediatric patients: Practical applications for gastrointestinal disorders and beyond: A narrative review

Nutrition in Clinical Practice, EarlyView.
Abstract Somatostatin is a naturally occurring polypeptide hormone that exerts its effect on the gastrointestinal tract by reducing exocrine and endocrine secretion, resulting in decreased motility, gastric emptying, splanchnic blood flow, fat absorption, lymphatic flow, and gallbladder contraction.
Bailey Dunn, Megan Foxe, Kathy Hunter Sprott, Jessica E. Hook, Candi Jump   +4 more
wiley   +1 more source

A geriatrician's approach to managing the complex older adult with obesity

Obesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

Tacrolimus‐Related Hepatic Sinusoidal Obstruction Syndrome in a Case Receiving Deceased Liver Donor Liver Transplantation

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yu‐Tsun Hsieh, Pier‐In Liang, Meng‐Hsuan Chiang   +2 more
wiley   +1 more source