Results 51 to 60 of about 1,416,559 (254)

Simultaneous Pancreas-Kidney and Pancreas Transplantation [PDF]

Journal of the American Society of Nephrology, 2001
The discovery of insulin in 1922 changed the treatment of type 1 diabetes mellitus (DM) forever. Insulin was the first effective therapy for type 1 DM; however, its success engendered a terrible paradox for patients with this disease.
Bryan N, Becker, Jon S, Odorico, Yolanda T, Becker, Marilyn, Groshek, Cathy, Werwinski, John D, Pirsch, Hans W, Sollinger   +6 more
openaire   +2 more sources

Exocrine drainage in vascularized pancreas transplantation in the new millennium.

World journal of transplantation, 2016
The history of vascularized pancreas transplantation largely parallels developments in immunosuppression and technical refinements in transplant surgery.
H. El-Hennawy, R. Stratta, Fowler R. Smith   +2 more
semanticscholar   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Assessing causal relationships between iron level, disorders of iron metabolism, and hepatocellular carcinoma: a Mendelian randomisation study

Discover Oncology
Background Emerging evidence indicates that elevated systemic iron levels and dysregulated iron metabolism are closely associated with the pathogenesis of hepatocellular carcinoma (HCC).
Sifan Dong, Xujia Wang, Shiqi An, Yongmei Hu, Junzhi Xiao, An Jiang   +5 more
doaj   +1 more source

C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms

Endocrine Connections, 2019
Objective: Elevated pre-operative C-reactive protein (CRP) serum values have been reported to be associated with poor overall survival for patients with pancreatic neuroendocrine neoplasms (pNEN).
Simon Schimmack, Yongchao Yang, Klaus Felix, Markus Herbst, Yixiong Li, Miriam Schenk, Frank Bergmann, Thilo Hackert, Oliver Strobel   +8 more
doaj   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Anti‐A Production by a Group 0 Spleen Transplanted to a Group A Recipient [PDF]

, 1985
. A group A1 diabetic received a pancreas‐spleen transplant from a group 0 donor. Severe immune hemolysis due to anti‐A ensued, requiring graft splenectomy. The transplanted spleen can be a potent source of blood group antibody. © 1985 S.
Beck, Bird, Bitter-Suermann, Contreras, Issitt, Marchioro, Ramsey, Starzl, Stevens, Widmann   +9 more
core   +1 more source

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo [PDF]

, 2019
The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these systems is lost upon isolation of the islets, and therefore the pathogenesis of diabetes can only
Conteh, Abass M., Day, Richard N., Dunn, Kenneth W., Kamocka, Malgorzata M., Linnemann, Amelia K., Martinez, Michelle M., Mirmira, Raghavendra G., Orr, Kara S., Piñeros, Annie R., Reissaus, Christopher A., Tersey, Sarah A., Twigg, Ashley N.   +11 more
core   +1 more source

Outcome of renal grafts after simultaneous kidney/ pancreas transplantation [PDF]

, 1991
Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique.
D. Abendroth, G. Hillebrand, H. Schneeberger, I. Petry, LA Castro, O Hillebrand, R. Landgraf, S. Schleibner, SJ Knechtle, W. -D. Illner, W. Land   +10 more
core   +1 more source

Pancreas Transplantation: Past, Present, Future.

American Journal of Medicine, 2016
Diabetes is the pandemic disease of the modern era, with 10% of these patients having type 1 diabetes mellitus. Despite the prevalence, morbidities, and associated financial burden, treatment options have not changed since the introduction of injectable ...
S. Dholakia, S. Mittal, I. Quiroga, J. Gilbert, E. Sharples, R. Ploeg, P. Friend   +6 more
semanticscholar   +1 more source