Results 191 to 200 of about 413,940 (274)

NF2 is Essential for Human Endoderm Development

Advanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong, Dongjun Han, Preetida Bhetariya, D. Bradley Welling, Miodrag Stojkovic, Konstantina M. Stankovic   +5 more
wiley   +1 more source

Deciphering of SOX9 Functions in Pancreatic Cancer Cells. [PDF]

Int J Mol Sci
Kashkin K, Kondratyeva L, Kopantzev E, Abramov I, Zhukova L, Chernov I.   +5 more
europepmc   +1 more source

A NEW APPROACH IN DIAGNOSIS FOR PANCREATIC CANCER BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

, 1982
Shuji Hirose, Haruo Funaki, Nobyoshi KIMURA   +2 more
openalex   +2 more sources

Insulin secretion and action in patients with pancreatic cancer [PDF]

, 1991
Eugênio Cersósimo, Peter W. T. Pisters, Gene R. Pesola, K. Mcdermott, Daiva Bajorunas, Murray F. Brennan   +5 more
openalex   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

Advanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang   +11 more
wiley   +1 more source

Immune-Based Strategies for Pancreatic Cancer in the Adjuvant Setting. [PDF]

Cancers (Basel)
Liang KL, Azad NS.
europepmc   +1 more source

Cost‐Effective Identification of Hepatocellular Carcinoma from Cirrhosis or Chronic Hepatitis Virus Infection Using Eight Methylated Plasma DNA Markers

Advanced Science, EarlyView.
Early detection of hepatocellular carcinoma in patients with liver cirrhosis and/or hepatitis virus B/C infection improves survival. Through marker discovery, 8 methylated DNA markers are identified and a logistic regression model (COMET‐LR) is built in the training set, which achieved 90.0% sensitivity at 97.4% specificity in the validation set.
Tian Yang, Mingda Wang, Nanya Wang, Mingxin Pan, Yu Xu, Qiancheng You, Lanqing Yao, Jiahao Xu, Lihui Gu, Xiaodong Sun, Lei Zhang, Jiayue Xu, Bingsi Li, Guoqiang Wang, Shangli Cai, Guoyue Lv, Feng Shen   +16 more
wiley   +1 more source

Advancing pancreatic cancer therapy by mesothelin-specific nanobody conjugation. [PDF]

Mol Cancer
Yi S, Noh K, Kim H, Jung E, Kim S, Lee J, Guk K, Choi J, Lim EK, Kim S, Park H, Lim JH, Jung CR, Kang T, Jung J.   +14 more
europepmc   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

The psychosocial impact of pancreatic cancer on caregivers: a scoping review. [PDF]

BMC Cancer
Anderson T, Mitchell G, Prue G, McLaughlin S, Graham-Wisener L.   +4 more
europepmc   +1 more source