Results 221 to 230 of about 749,373 (347)

Can Symptom Clusters Predict Stage, Resectability, and Survival in Pancreatic Cancer? [PDF]

Cancer Manag Res
Demir MS, Ağdaş G.
europepmc   +1 more source

Combined treatment with tamoxifen and a fusicoccin derivative (ISIR-042) to overcome resistance to therapy and to enhance the antitumor activity of 5-fluorouracil and gemcitabine in pancreatic cancer cells

, 2015
Takaaki Miyake, Yoshio Honma, Takeshi Urano, Nobuo Kato, Junji Suzumiya   +4 more
openalex   +2 more sources

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Deciphering the liver's role in pancreatic cancer metastasis: pathways and therapeutic approaches. [PDF]

NPJ Precis Oncol
Inzunza J, Del Valle AC.
europepmc   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Pancreatic Cancer in Cystic Fibrosis: Is the Incidence Increasing? [PDF]

Pediatr Pulmonol
Markham R, Wright BA, Pena T.
europepmc   +1 more source

Fraction B From Catfish Epidermal Secretions Kills Pancreatic Cancer Cells, Inhibits CD44 Expression and Stemness, and Alters Cancer Cell Metabolism

, 2021
Jassim M. Al‐Hassan, Daoyan Wei, Sharmistha Chakraborty, Tara Conway, Patrea R. Rhea, Bo Wei, Megan Tran, Mihai Gagea, Mohammad Afzal, Sosamma Oommen, Divya Nair, Bincy Paul, Peiying Yang   +12 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Tryptophan metabolism in pancreatic cancer: A review. [PDF]

Medicine (Baltimore)
Gao Y, Yang L, Wang X.
europepmc   +1 more source

Dysplastic nevus syndrome and pancreatic cancer: A case report

, 2021
Liliana Gabriela Popa, Călin Giurcăneanu, Cornelia Niţipir, Ana Maria Popa, Cristiana Stoica, Cristina Beiu, Tiberiu Tebeică, Silvius Negoiţă, Mara Mădălina Mihai   +8 more
openalex   +2 more sources