Results 221 to 230 of about 5,109,346 (334)

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

open access: yesNature Cell Biology, 2015
B. Costa-Silva   +36 more
semanticscholar   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

open access: yesAdvanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma   +9 more
wiley   +1 more source

Discovery of a novel RSK2 inhibitor for the treatment of metastatic pancreatic cancer. [PDF]

open access: yesJ Enzyme Inhib Med Chem
Chung CH   +5 more
europepmc   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

open access: yesAdvanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Cancer Vaccination and Immune-Based Approaches in Pancreatic Cancer. [PDF]

open access: yesCancers (Basel)
Bloom M   +4 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Drugging the 'undruggable' KRAS: breakthroughs, challenges, and opportunities in pancreatic cancer. [PDF]

open access: yesCancer Biol Med
Khan N   +7 more
europepmc   +1 more source

Insulin secretion and action in patients with pancreatic cancer [PDF]

open access: bronze, 1991
Eugênio Cersósimo   +5 more
openalex   +1 more source

Early Pancreatic Cancer Diagnosis via Ultrasensitive THz Toroidal Metasensing

open access: yesAdvanced Photonics Research, EarlyView.
This study introduces a revolutionary terahertz metasurface biosensor using gold nanoparticles to boost sensitivity. It achieves precise detection of ultra‐low biomarker concentrations (1–1000 pg mL−1) with a 97.6 GHz/RIU sensitivity through optimized antibody binding.
Peng Wang   +8 more
wiley   +1 more source

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