Results 31 to 40 of about 68,621 (229)

Main-duct intraductal papillary mucinous neoplasm of the pancreas: a case report

open access: yesClinical Management Issues, 2012
Three distinct entities among non-inflammatory cystic lesions of the pancreas have been defined: intraductal papillary mucinous neoplasm (IPMN), serous cystic neoplasm (SCN) and mucinous cystic neoplasm (MCN).
Natalia Manetti   +6 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Rare Pancreatic Tumors

open access: yesJournal of Gastrointestinal and Abdominal Radiology, 2020
Pancreatic ductal adenocarcinoma, neuroendocrine tumor, and cystic pancreatic neoplasms are the common pancreatic tumors most radiologists are familiar with.
Amitkumar Choudhari   +5 more
doaj   +1 more source

Insights into the Pathogenesis of Pancreatic Cystic Neoplasms [PDF]

open access: yesDigestive Diseases and Sciences, 2017
With the current epidemic of diagnosed pancreatic cystic neoplasms on the rise, a substantial amount of work has been done to unravel their biology, thus leading to implications on clinical decision making. Recent genetic profiling of resected human specimens has identified alterations in signaling pathways involving KRAS and GNAS signaling as early ...
Vrishketan, Sethi   +3 more
openaire   +2 more sources

Pancreatic Cystic Neoplasms: Diagnosis and Management

open access: yesDiagnostics, 2023
Pancreatic cancer is one of the most lethal cancers, largely related to the difficulties with early detection, as it typically presents in later stages. Pancreatic cystic neoplasms (PCN) are commonly diagnosed as incidental findings on routine imaging.
Abigail Schubach   +2 more
openaire   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran   +15 more
wiley   +1 more source

Radical surgery following inadequate drainage procedures for cystic neoplasms of the pancreas

open access: yesКлиническая практика
BACKGROUND: Despite the presence of national and international recommendations on the diagnostics and treatment of cystic lesions in the pancreas, the consequences of inappropriate drainage procedures for pancreatic cystic neoplasms mistaken for the post-
Pavel V. Markov   +5 more
doaj   +1 more source

A RARE CLINICAL CASE OF MIXED SEROUS NEUROENDOCRINE CYSTIC NEOPLASM OF THE PANCREAS

open access: yesСибирский онкологический журнал, 2018
Background. Serous cystic pancreatic neoplasm is a rare pancreatic tumor, accounting for 1–2 % of all pancreatic tumors. In 2010,  mixed serous neuroendocrine cystic neoplasia was included into the classification of the WHO for pancreatic tumors.
A. P. Koshel   +5 more
doaj   +1 more source

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