Results 191 to 200 of about 201,651 (253)

Effects of proton therapy on the tumor immune system and clinical implications: A review

Precision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu, Mei Tao, Min Fu, Yingjia Hu, Zhen Tao, Guangyuan Hu   +5 more
wiley   +1 more source

Rare Cutaneous Metastasis From Esophageal Squamous Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
Sarah Hsin Cheng, Yen‐Shuo Huang, Chi‐En Hsiao, Hui‐Hua Hsiao   +3 more
wiley   +1 more source

Latin America's First Active and Intelligent Packaging for Organ Transportation

Packaging Technology and Science, EarlyView.
The graphical abstract features Latin America's first active and intelligent packaging for organ transportation (EMAIS‐SR). The image illustrates the device alongside its core features: active temperature control, real‐time monitoring, autonomous battery‐powered operation and biological safety.
Sibele Maria Schuantes‐Paim, Renata Fabiana Leite, Victor Arayama Cruz, Vanessa Ayres Carneiro Gonçalves, Júlia Karini da Silva Araujo, Karoline Sabrina de Carvalho Gomes, Luciana Chelotti Cardim Perillo, Graciana Maria de Moraes Coutinho, Eliana Cavalari Teraoka, Adriana Aparecida Carbonel, José Homero Soares, Manuel de Jesus Simões, Selma Ferrer, Ari Nelson Rodrigues Costa, Ana Paula Reis Nolêtto, Leandro Moriyama Konatu, Murched Omar Taha, André Ibrahim David, Janine Schirmer, Bartira de Aguiar Roza   +19 more
wiley   +1 more source

A Biomimetic Breast Tumor‐On‐Chip Platform Reveals Mesenchymal Marker Upregulation Following Gold Nanorod Photothermal Therapy

Small, EarlyView.
A biomimetic microfluidic tumor‐on‐chip platform was designed to uncover subtype‐dependent responses to nanoparticle‐mediated photothermal therapy in breast cancer spheroids. The platform establishes a physiologically relevant and controllable 3D system for precision evaluation of nanophotothermal cancer therapies.
Camila A. Salvego, Hasti Honari, Anastasiia Dubrova, Stéphanie Descroix, Martha S. Ribeiro, Aurore V. Walle, Claire Wilhelm   +6 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Small Bowel Cancer: Implications of Preoperative Work‐Up on Surgical Strategy

World Journal of Surgery, EarlyView.
Small bowel cancers comprise a heterogeneous group of malignancies, making diagnosis and treatment challenging. This study aimed to evaluate the ability of preoperative diagnostic work‐up to predict clinical and histopathological findings, facilitate subgroup identification, and support tailored, individualized surgical strategies. Preoperative work‐up
Erik Kjæstad, Espen Thiis‐Evensen, Anita Sveen, Arne Olav Bakka, Johannes Kurt Schultz   +4 more
wiley   +1 more source