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The role of pancreatic polypeptide in pancreatic diseases [PDF]

Advances in Clinical and Experimental Medicine, 2017
The aim of this study was to review the diagnostic significance of pancreatic polypeptide (PP) in pancreatic diseases. PP may play a significant role in monitoring the development of the disease and the patient's healing process, particularly after the removal of a portion of the pancreas. Determining PP in acute pancreatitis is quite controversial. At
Grzegorz Marek, Mariola Śliwińska-Mossoń, Halina Milnerowicz   +2 more
openaire   +4 more sources

THE "PANCREATIC REACTION" IN ABDOMINAL DISEASE [PDF]

BMJ, 1910
W. M. S. Russell
openalex   +5 more sources

Case Report: Partial response to single-agent pembrolizumab in a chemotherapy-resistant metastatic pancreatic cancer patient with a high tumor mutation burden

Frontiers in Oncology, 2023
Single-agent immune checkpoint blockade has shown no clinical benefits in pancreatic cancer. Recently, the programmed cell death protein 1 (PD-1) antibody pembrolizumab has been recommended as a treatment option for high tumor mutational burden (TMB ...
Mengyao Dai, Mengyao Dai, Mengyao Dai, Mengyao Dai, Jianpeng Sheng, Jianpeng Sheng, Jianpeng Sheng, Qi Zhang, Qi Zhang, Qi Zhang, Qi Zhang, Jianxin Wang, Jianxin Wang, Jianxin Wang, Jianxin Wang, Qihan Fu, Qihan Fu, Qihan Fu, Qihan Fu, Tingbo Liang, Tingbo Liang, Tingbo Liang, Tingbo Liang   +22 more
doaj   +1 more source

Positive feedback between lncRNA FLVCR1-AS1 and KLF10 may inhibit pancreatic cancer progression via the PTEN/AKT pathway

Journal of Experimental & Clinical Cancer Research, 2021
Background FLVCR1-AS1 is a key regulator of cancer progression. However, the biological functions and underlying molecular mechanisms of pancreatic cancer (PC) remain unknown.
Jiewei Lin, Shuyu Zhai, Siyi Zou, Zhiwei Xu, Jun Zhang, Lingxi Jiang, Xiaxing Deng, Hao Chen, Chenghong Peng, Jiaqiang Zhang, Baiyong Shen   +10 more
doaj   +1 more source

A case of walled‐off necrosis extending into the pelvic cavity successfully treated by endoscopic necrosectomy using a lumen‐apposing metal stent

DEN Open, 2022
A 31‐year‐old man developed massive walled‐off necrosis extending into the pelvic cavity following severe acute alcoholic pancreatitis. Endoscopic ultrasound‐guided fistula drainage was performed using a lumen‐apposing metal stent, but this was ...
Makoto Morita, Tomoyuki Yokota, Ryo Yano, Michiko Amano, Hironori Ochi, Nobuaki Azemoto, Toshie Mashiba, Kouji Joko   +7 more
doaj   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

Journal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu, Minmin Shi, Xingfeng He, Yizhi Cao, Pengyi Liu, Fanlu Li, Siyi Zou, Chenlei Wen, Qian Zhan, Zhiwei Xu, Jiancheng Wang, Baofa Sun, Baiyong Shen   +12 more
doaj   +1 more source

Real‐world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma

Cancer Medicine, 2023
Background The American Joint Committee on Cancer (AJCC) tumor‐node‐metastasis (TNM) staging system focuses on traditional biological factors (BFs). The present study incorporates nonbiological factors (NBFs) into the AJCC‐TNM staging system in terms of ...
Chao Wang, Haoda Chen, Xiaxing Deng, Wei Xu, Baiyong Shen   +4 more
doaj   +1 more source

Establishment of a 3D culture model in vitro of pancreatic cancer primary cells using hydrogel microspheres

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To establish an in vitro culture model mimicking tumor microenvironment using hydrogel microspheres and fresh primary pancreatic cancer cells.Methods·The morphological distribution of the hydrogel microspheres was recorded, observed and ...
MA Fangfang, QIN Jiejie, REN Lingjie, TANG Xiaomei, LIU Jia, SHI Minmin, JIANG Lingxi   +6 more
doaj   +1 more source

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma

Journal of Translational Medicine, 2020
Background Cancer stem cells (CSCs) are crucial to the malignant behaviour and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). In recent years, CSC biology has been widely studied, but practical prognostic signatures based on CSC-related genes
Zengyu Feng, Minmin Shi, Kexian Li, Yang Ma, Lingxi Jiang, Hao Chen, Chenghong Peng   +6 more
doaj   +1 more source

Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway

International Journal of Endocrinology, 2023
Purpose. This study aimed to investigate the potential mechanism underlying the therapeutic effect of sildenafil in combination with islet transplantation for diabetic peripheral neuropathy. Methods.
Xiandong Zhu, Shangjing Xie, Jiawei Chen, Qiaohong Lu, Xiaowu Wang, Feixiang Duan, Sinian Xu, Yan Zhang, Hongjian Huang, Yongqiang Wang, Hongwei Wang, Bicheng Chen, Huanjie Huang   +12 more
doaj   +1 more source