Results 181 to 190 of about 461,778 (284)

Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study. [PDF]

Front Immunol, 2023
Yuan S, Miao Y, Ruan X, Chen J, Li X, Larsson SC.   +5 more
europepmc   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

The role of autophagy in pancreatic diseases. [PDF]

Front Pharmacol
Zhang WG, Wu QZ, Shao BZ.
europepmc   +1 more source

Impact of the COVID-19 Pandemic on the Management of Gallbladder, Biliary Tract, and Pancreatic Diseases. [PDF]

Cureus, 2023
Ilyas Khan A, Thomas C, O'Connor H, Dowker F, Horgan L, Khan MA.   +5 more
europepmc   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Increased thromboembolic risk in non-neoplastic pancreatic diseases: A review focusing on acute pancreatitis. [PDF]

Niger Med J
Odusanya KE, Ukoha CB, Olomojobi VO, Okpanachi PA, Adabiri JO, Okeugo OT, Quadri IO.   +6 more
europepmc   +1 more source

Understanding Necroptosis in Pancreatic Diseases. [PDF]

Biomolecules, 2022
He R, Wang Z, Dong S, Chen Z, Zhou W.
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

European Registry of Hereditary Pancreatic Diseases (EUROPAC): protocol for primary and secondary screening in individuals with inherited pancreatic disease syndromes for pancreatic ductal adenocarcinoma and complications of other pancreatic diseases. [PDF]

BMJ Open
Boughey A, Hopley P, Sarantitis I, Thomas P, Gubacsi B, Jevons K, Crowe E, Hughes E, Quinn I, Royle L, Jackson RJ, Greenhalf W, Halloran C.   +12 more
europepmc   +1 more source

Optimal glycated hemoglobin A1c value for prediabetes and diabetes in patients with pancreatic diseases. [PDF]

Front Endocrinol (Lausanne), 2023
Chen G, Zhang R, Tan C, Liu X, Yu L, Chen Y.   +5 more
europepmc   +1 more source