Results 221 to 230 of about 466,398 (341)

Disease-free survival as a surrogate endpoint for overall survival in adjuvant trials of pancreatic cancer: evidence from 20 randomized controlled trials [PDF]

, 2020
Run‐Cong Nie, Xuebin Zou, Shuqiang Yuan, Ying-Bo Chen, Shi Chen, Yongming Chen, Guoming Chen, Xiao‐Jiang Chen, Tianqi Luo, Shuman Li, Jin‐Ling Duan, Yun Wang, Yuanfang Li   +12 more
openalex   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Technical success, clinical efficacy, and safety of endoscopic minor papilla interventions for symptomatic pancreatic diseases. [PDF]

World J Gastroenterol
Ren X, Qu YP, Xia T, Tang XF.
europepmc   +1 more source

Multiple roles for cholinergic signaling in pancreatic diseases. [PDF]

World J Gastroenterol, 2022
Yang JM, Yang XY, Wan JH.
europepmc   +1 more source

Screening for Pancreatic Adenocarcinoma in BRCA2 Mutation Carriers: Results of a Disease Simulation Model [PDF]

, 2015
Pari V. Pandharipande, Alvin Jeon, Curtis R. Heberle, Emily C. Dowling, Chung Yin Kong, Daniel C. Chung, William R. Brugge, Chin Hur   +7 more
openalex   +1 more source

Clinofibrate Disrupts the SNORA80B/YTHDC1‐Driven M6A Modification to Suppress Cholesterol Metabolism and Cisplatin Resistance in ESCC

Advanced Science, EarlyView.
This study uncovers a non‐canonical role of SNORA80B in ESCC, showing it mediates AR‐driven metabolic reprogramming via N⁶‐methyladenosine (m6A) methylation. By binding YTHDC1, SNORA80B stabilizes cholesterol‐metabolic enzyme mRNAs and promotes tumor progression. The FDA‐approved drug clinofibrate inhibits SNORA80B by disrupting cholesterol homeostasis,
Hongyu Yuan, Ge Ge, LiQiu Liu, Sijun Hu, Miaomiao Tian, Yongzhan Nie, Zitong Zhao, Yongmei Song   +7 more
wiley   +1 more source

Correlation Between Fatty Pancreas Disease and Pancreatic Diseases, Perioperative Complications of Pancreatic Surgery. [PDF]

Cancer Manag Res
Wu Z, Li J.
europepmc   +1 more source

Application of exosomes in the diagnosis and treatment of pancreatic diseases. [PDF]

Stem Cell Res Ther, 2022
Han L, Zhao Z, Yang K, Xin M, Zhou L, Chen S, Zhou S, Tang Z, Ji H, Dai R.   +9 more
europepmc   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Role of Sphingosine-1-Phosphate Signaling Pathway in Pancreatic Diseases. [PDF]

Int J Mol Sci
Fu F, Li W, Zheng X, Wu Y, Du D, Han C.
europepmc   +1 more source