Results 251 to 260 of about 9,818,371 (382)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan   +12 more
wiley   +1 more source

Early Pancreatic Cancer Diagnosis via Ultrasensitive THz Toroidal Metasensing

open access: yesAdvanced Photonics Research, EarlyView.
This study introduces a revolutionary terahertz metasurface biosensor using gold nanoparticles to boost sensitivity. It achieves precise detection of ultra‐low biomarker concentrations (1–1000 pg mL−1) with a 97.6 GHz/RIU sensitivity through optimized antibody binding.
Peng Wang   +8 more
wiley   +1 more source

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