Results 261 to 270 of about 466,398 (341)

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Global trends in the application of fluorescence imaging in pancreatic diseases: a bibliometric and knowledge graph analysis. [PDF]

Front Oncol
Luo Q, Teng X, Dai M, Yang J, Cheng W, Chen K, Zhou L.   +6 more
europepmc   +1 more source

Deep Learning‐Powered Nanoplasmonic Biosensing Approach Enables Ultrasensitive Extracellular Vesicles Profiling for Cancer Screening

Advanced Science, EarlyView.
This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu, Yingqi Xiao, Xinyue Huang, Qiang Niu, Lihuang Zeng, Shaowei Lin, Mengqi Jiang, Tianhao Huang, Hanyang Chen, Yinong Xie, Yuan Gao, Wei Chen, Yiming Yan, Jiaqing Shen, Kaibin Chen, Yurong Dai, Zhipeng Zhang, Lijun Zeng, Yahong Chen, Boan Li, Jinfeng Zhu, Bo Li   +21 more
wiley   +1 more source

Pancreatic Diseases: Genetics and Modeling Using Human Pluripotent Stem Cells. [PDF]

Int J Stem Cells
Lee Y, Lee K.
europepmc   +1 more source

Synergistic Anti‐Cancer Therapy Through Ultrasound‐Induced Piezocatalytic Therapy and Tumor Treatment Fields

Advanced Science, EarlyView.
A novel, wearable anti‐cancer platform synergistically combines tumor treating fields (TTFs) and piezocatalytic therapy (PCT) via ultrasound‐activated, lead‐free piezocomposites. This strategy efficiently suppresses tumor growth, modulates the immune microenvironment, and demonstrates strong therapeutic synergy in both mouse model of subcutaneous tumor
Jing Jin, Haoyue Xue, Keliang Chen, Yonglin Su, Xin Hu, Xiaolin Hu, Xing Huang, Laiming Jiang, Jiagang Wu, Xingchen Peng   +9 more
wiley   +1 more source

Sedative effects of propofol and risk factors for excessive sedation in the endoscopic treatment of biliary and pancreatic diseases. [PDF]

DEN Open
Maruki Y, Hijioka S, Yagi S, Takasaki T, Chatto M, Fukuda S, Yamashige D, Okamoto K, Agarie D, Hara H, Hagiwara Y, Nagashio Y, Morizane C, Sone M, Okusaka T, Saito Y.   +15 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Pro-Inflammatory Food, Gut Microbiota, and Cardiovascular and Pancreatic Diseases. [PDF]

Biomolecules
Chen B, Patel S, Bao L, Nadeem D, Krittanawong C.   +4 more
europepmc   +1 more source

Pancreatic tuberculosis – A common disease at a rare site diagnosed on cytology

Paruvathavarthini Thambiraj, Vijayalakshmi Gudivada, Debasis Gochhait, Neelaiah Siddaraju, Biju Pottakat   +4 more
openalex   +1 more source

Prevalence of S and Z alpha 1-antitrypsin mutations in patients with pancreatic diseases in Serbian population

, 2010
Aleksandra Nikolić, Aleksandra Divac Rankov, Marija Stanković, Jelena Dinić, Snežana Lukić, Marina Andjelic‐Jelic, Dragan Popović, Dragica Radojković   +7 more
openalex   +2 more sources