Results 31 to 40 of about 461,778 (284)

Immunity-Related Gene Signature Identifies Subtypes Benefitting From Adjuvant Chemotherapy or Potentially Responding to PD1/PD-L1 Blockage in Pancreatic Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Tumor microenvironment comprises of a variety of cell types, which is quite complex and involved in chemotherapy and immune checkpoint blockage resistance.
Hao Qian   +31 more
doaj   +1 more source

Nucleosomes in pancreatic cancer patients during radiochemotherapy [PDF]

open access: yes, 2005
Nucleosomes appear spontaneously in elevated concentrations in the serum of patients with malignant diseases as well as during chemo- and radiotherapy. We analyzed whether their kinetics show typical characteristics during radiochemotherapy and enable an
Amoura Z   +19 more
core   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

open access: yes, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D   +10 more
core   +1 more source

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

open access: yes, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A.   +8 more
core   +1 more source

Adjuvant Transarterial Chemoembolization for Barcelona Clinic Liver Cancer Stage A Hepatocellular Carcinoma After Hepatectomy

open access: yesFrontiers in Oncology, 2020
IntroductionThe care for patients with hepatocellular carcinoma (HCC) is challenging. This study is to evaluate the effect of adjuvant transarterial chemoembolization (TACE) for Barcelona Clinic Liver Cancer (BCLC) stage A HCC patients after hepatectomy ...
Yue-Lin Zhang   +27 more
doaj   +1 more source

Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]

open access: yes, 2002
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes   +5 more
core   +1 more source

Primary hyperparathyroidism can generate recurrent pancreatitis and secondary diabetes mellitus – A case report [PDF]

open access: yes, 2019
Introduction. Acute or recurrent pancreatitis may be a complication of primary hyperparathyroidism and patients with previous episodes of pancreatitis may develop secondary diabetes mellitus. Case report.
Dănciulescu Miulescu, Rucsandra Elena   +4 more
core   +2 more sources

Development of a Novel Evaluation Method for Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Pancreatic Diseases Using Artificial Intelligence

open access: yesDiagnostics, 2022
We aimed to develop a new artificial intelligence (AI)-based method for evaluating endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) specimens in pancreatic diseases using deep learning and contrastive learning.
Takuya Ishikawa   +8 more
doaj   +1 more source

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]

open access: yes, 2010
ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E   +7 more
core   +2 more sources

Sintilimab-Induced Autoimmune Diabetes in a Patient With the Anti-tumor Effect of Partial Regression

open access: yesFrontiers in Immunology, 2020
ContextImmune checkpoint blockades (ICBs) have been approved widely to treat various malignancies. Autoimmune diabetes mellitus, which can be caused by programmed cell death protein 1 (PD-1) inhibitors, is rare.
Liang Wen   +18 more
doaj   +1 more source

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