Results 191 to 200 of about 217,476 (395)

Early detection of pancreatic ductal adenocarcinomas with an ensemble learning model based on a panel of protein serum biomarkers

, 2021
Nuno R. Nené, Alexander Ney, Tatiana Nazarenko, Oleg Blyuss, Harvey E. Johnston, Harry J. Whitwell, Eva Sedlak, Aleksandra Gentry‐Maharaj, Eithne Costello, William Greenhalf, Ian Jacobs, Usha Menon, J. Justin Hsuan, Stephen P. Pereira, Alexey Zaikin, John F. Timms   +15 more
openalex   +1 more source

Proteogenomic characterization of pancreatic ductal adenocarcinoma

Cell, 2021
L. Cao, Chen Huang, D. Zhou, Yingwei Hu, T. M. Lih, Sara R. Savage, Karsten Krug, D. Clark, M. Schnaubelt, Lijun Chen, F. Leprevost, R. V. Eguez, Weiming Yang, Jianbo Pan, Bo Wen, Yongchao Dou, Wen Jiang, Yuxing Liao, Zhiao Shi, N. Terekhanova, Song Cao, Rita Jui-Hsien Lu, Yize Li, Ruiyang Liu, Houxiang Zhu, Peter Ronning, Yige Wu, Matthew A. Wyczalkowski, H. Easwaran, Ludmila V. Danilova, A. Mer, S. Yoo, Joshua M Wang, Wenke Liu, B. Haibe-Kains, M. Thiagarajan, S. Jewell, G. Hostetter, Chelsea J. Newton, Q. K. Li, M. Roehrl, D. Fenyö, Pei Wang, A. Nesvizhskii, D. Mani, G. Omenn, Emily Boja, M. Mesri, A. Robles, H. Rodriguez, O. Bathe, D. Chan, R. Hruban, L. Ding, Bing Zhang, Hui Zhang, Mitual B. Amin, E. An, Christine Ayad, Thomas Bauer, Chet Birger, M. Birrer, S. Boca, William Bocik, M. Borucki, S. Cai, Steve Carr, Sandra R. Cerda, Huan Chen, Steven F. Chen, David W. Chesla, A. Chinnaiyan, A. Colaprico, S. Cottingham, Magdalena Derejska, S. Dhanasekaran, M. Domagalski, B. Druker, Elizabeth Duffy, Maureen A. Dyer, Nathan J. Edwards, M. Ellis, J. Eschbacher, Alicia Francis, Jesse Francis, S. Gabriel, N. Gabrovski, J. Gardner, G. Getz, Michael A. Gillette, C. A. Goldthwaite, Pamela Grady, Shuai Guo, P. Hariharan, Tara Hiltke, B. Hindenach, K. Hoadley, Jasmine Huang, Corbin D. Jones, K. Ketchum, C. Kinsinger, J. Koziak, K. Kuśnierz, Tao Liu, J. Long, D. Mallery, S. Mareedu, R. Matteotti, Nicollette Maunganidze, P. McGarvey, P. Minoo, O. Paklina, A. Paulovich, S. Payne, O. Potapova, B. Pruetz, L. Qi, Nancy V. Roche, K. Rodland, D. Rohrer, E. Schadt, A. Shabunin, T. Shelton, Y. Shutack, Shilpi Singh, Michael V. Smith, Richard D. Smith, L. Sokoll, J. Suh, Ratna R. Thangudu, S. Tsang, K. S. Um, Dana R. Valley, Negin Vatanian, Wenyi Wang, G. Wilson, M. Wiznerowicz, Zhen Zhang, Grace Zhao   +138 more
semanticscholar   +1 more source

Learning Curve Effect in Reducing Local Recurrence Rate After Resection of Pancreatic Cancer With Arterial Abutment: A Single‐Center Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida, Hirochika Toyama, Takayuki Kodama, Yoshihide Nanno, Takuya Mizumoto, Shohei Komatsu, Hiroaki Yanagimoto, Masahiro Kido, Tomoo Ito, Takumi Fukumoto   +9 more
wiley   +1 more source

Unexpectedly High Incidence of Immune‐Related Adverse Events in Gastric Cancer Patients Who Received Conversion Surgery After Nivolumab‐Including Chemotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Nivolumab‐including chemotherapy (nivo‐CTX) for stage IV gastric cancer (GC) may increase the chance of conversion surgery but risk of immune‐related adverse events (irAEs) during perioperative period remains unclear. Methods We examined irAEs in 36 patients with marginally resectable GC who received nivo‐CTX followed by surgery ...
Masashi Nishino, Takaki Yoshikawa, Hirokazu Shoji, Yuki Takenaka, Maho Takuwa, Yurina Fujisaki, Rei Ogawa, Takeyuki Wada, Tsutomu Hayashi, Yukinori Yamagata, Nobuyoshi Hiraoka, Yasuyuki Seto   +11 more
wiley   +1 more source

Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer

Tumor Biology, 2018
Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Mira A Lanki, Hanna E Seppänen, Harri K Mustonen, Camilla Böckelman, Anne T Juuti, Jaana K Hagström, Caj H Haglund   +6 more
doaj   +1 more source

Supplementary Tables S1 - S5 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade

, 2023
Hayden Pearce, Wayne Croft, Samantha M. Nicol, Sandra Margielewska‐Davies, Richard Powell, Richard J. Cornall, Simon J. Davis, Francesca Marcon, Matthew Pugh, Éanna Fennell, Sarah Powell‐Brett, Brinder S. Mahon, Rachel M. Brown, Gary Middleton, Keith Roberts, Paul Moss   +15 more
openalex   +1 more source

Outcomes of Pancreas‐Sparing Total Duodenectomy for Severe Duodenal Polyposis in Patients With Familial Adenomatous Polyposis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Spigelman stage IV duodenal polyposis (SP‐stage IV DP) is associated with high duodenal cancer risk in patients with familial adenomatous polyposis (FAP). This study evaluated the surgical and oncological outcomes of pancreas‐sparing total duodenectomy (PSTD) as a surgical prophylaxis for severe duodenal polyposis in FAP.
Takehiro Shiraishi, Hideyuki Ishida, Takatoshi Matsuyama, Noriyasu Chika, Yoshiko Mori, Norimichi Chiyonobu, Youichi Kumagai, Ibuki Fujinuma, Toshiro Ogura   +8 more
wiley   +1 more source

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C, Kelsey, Karl T, Koestler, Devin C, Salas, Lucas A, Wiencke, John K, Zhang, Ze   +5 more
core  

Increase in Pancreatoduodenectomy Volume at Mid‐Volume Facilities in the United States: A National Cancer Database Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The annual number of pancreatoduodenectomies (PDs) in the United States has increased over the past decade, but the facility types driving this growth and whether outcomes have improved remain unclear. We aimed to identify characteristics of facilities with increasing PD volumes and assess national trends in centralization ...
Koichi Tomita, Naruhiko Ikoma
wiley   +1 more source

Insulin-Like Growth Factor-1 Receptor Expression and Disease Recurrence and Survival in Patients with Resected Pancreatic Ductal Adenocarcinoma

, 2020
Chunxia Du, Annacarolina da Silva, Vicente Morales‐Oyarvide, Andressa Dias Costa, Margaret M. Kozak, Richard F. Dunne, Douglas A. Rubinson, Kimberly Perez, Yohei Masugi, Tsuyoshi Hamada, Lauren K. Brais, Chen Yuan, Ana Babić, Matthew D. Ducar, Aaron R. Thorner, Andrew J. Aguirre, Matthew H. Kulke, Kimmie Ng, Thomas E. Clancy, Jennifer J. Findeis-Hosey, Daniel T. Chang, Jason L. Hornick, Charles S. Fuchs, Shuji Ogino, Albert C. Koong, Aram F. Hezel, Brian M. Wolpin, Jonathan A. Nowak   +27 more
openalex   +2 more sources