Results 201 to 210 of about 84,228 (303)

Initial Site of Metastasis Influences Prognosis in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Med
Mancheski E, Baek D, Bowne W, Lavu H, Yeo CJ, Nevler A.   +5 more
europepmc   +1 more source

Transcriptomic comparative study between canalicular adenoma and HMGA2::WIF1 canalicular‐like pleomorphic adenoma

The Journal of Pathology, EarlyView.
Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair, Anne Champagnac, Maxime Fieux, Pierre Philouze, Philippe Ceruse, Brice Thamphya, Daniel Pissaloux, Franck Tirode, Nazim Benzerdjeb   +8 more
wiley   +1 more source

Perioperative Thyroid-Metabolic Changes in Pancreatic Ductal Adenocarcinoma According to Surgical Management. [PDF]

Cancers (Basel)
Grząsiak-Kraj O, Kraj T, Majos A, Wardęszkiewicz A, Szmiel A, Poznański K, Durczyński A, Hogendorf P, Strzelczyk J.   +8 more
europepmc   +1 more source

Targeting fibrosis in the treatment of lower urinary tract dysfunction

The Journal of Pathology, EarlyView.
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar, Sophia M Vrba, Emily A Ricke, Zsuzsanna Fabry, Matthew S Lee, Kevin T McVary, William A Ricke   +6 more
wiley   +1 more source

Emerging precision therapeutics for pancreatic ductal adenocarcinoma: KRAS and beyond. [PDF]

Ther Adv Med Oncol
Misirian A, Pai J, Hanna DL.
europepmc   +1 more source

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

The Journal of Pathology, EarlyView.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup, Julian Dosch, Christopher Dietz‐Fricke, Sara Khosraviseftejani, Esther Engel, Adalbert F de Valk, Dominic Menger, Patrick Welker, Peter J Wild, Kilian B Kennel, Maja Kantlehner, Paul K Ziegler, Florian R Greten   +12 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Epigenetic Regulators as Therapeutic Targets in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancers (Basel)
Kubiak K, Inkielewicz-Stępniak I.
europepmc   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Repurposing Rilmenidine as a Potential Antimetastatic Therapy Targeting Nischarin in Pancreatic Ductal Adenocarcinoma. [PDF]

Cells
Živić K, Pavlović M, Ostojić M, Galun D, Pavić A, Srdić-Rajić T, Grahovac J.   +6 more
europepmc   +1 more source