bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang +5 more
wiley +1 more source
pH-Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma. [PDF]
Schwab A +37 more
europepmc +1 more source
Le cancer du pancréas est la quatrième cause de décès par cancer. L'échoendoscopie avec cytoponction est une technique qui va permettre à la fois de caractériser un syndrome de masse pancréatique mais aussi de réaliser un prélèvement biopsique pour ...
Bournet, Barbara
core
Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics
Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley +1 more source
PPARδ: An underappreciated tumor accelerator in pancreatic ductal adenocarcinoma. [PDF]
Niu D +5 more
europepmc +1 more source
Biomarkers for the Early Detection of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma has one of the worst survival rates among adult cancers, with only 11% in the United States surviving five years after diagnosis.
Mellby, Linda D. +2 more
core +1 more source
Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu +13 more
wiley +1 more source
Sarcopenia as a Marker of Immunometabolic Vulnerability in Pancreatic Ductal Adenocarcinoma. [PDF]
Karthik M +4 more
europepmc +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Gastric metastasis from pancreatic ductal adenocarcinoma: a case report. [PDF]
Urano T +9 more
europepmc +1 more source

