Results 221 to 230 of about 217,476 (395)

Figure S3 from Targeting the IGF-Axis Potentiates Immunotherapy for Pancreatic Ductal Adenocarcinoma Liver Metastases by Altering the Immunosuppressive Microenvironment

, 2023
Masakazu Hashimoto, John David Konda, Stéphanie Perrino, María Celia Fernández, Andrew M. Lowy, Pnina Brodt   +5 more
openalex   +1 more source

Elevated MCP-1 is associated with cancer cachexia in patients with pancreatic ductal adenocarcinoma [PDF]

, 2017
Mary Dillhoff, Heather L. Lewis, Ericka Haverick, Phil A. Hart, Andrei Manilchuk, Timothy M. Pawlik, Charlie Schmidt, Erin E. Talbert, Denis C. Guttridge   +8 more
openalex   +1 more source

Supplemental Figure 1 from Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma

, 2023
Jenifer B. Gifford, Wei Huang, Ann E. Zeleniak, Antreas Hindoyan, Hong Wu, Timothy R. Donahue, R. J. Hill   +6 more
openalex   +1 more source

Targeting KRAS in Pancreatic Ductal Adenocarcinoma: The Long Road to Cure [PDF]

, 2023
Victor Hugo Fonseca de Jesus, Maria Cecília Mathias-Machado, João Paulo Fogacci de Farias, Marcelo Porfírio Sunagua Aruquipa, Alexandre A. Jácome, Renata D’Alpino Peixoto   +5 more
openalex   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Supplementary Table S3 from Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma

, 2023
Xin Wang, Ana P. Kutschat, Joana Aggrey-Fynn, Feda H. Hamdan, Rondell P. Graham, Alexander Q. Wixom, Yara Souto, Swetlana Ladigan‐Badura, Jennifer A. Yonkus, Amro M. Abdelrahman, Roberto Alva‐Ruiz, Jochen Gaedcke, Philipp Ströbel, Robyn Laura Kosinsky, Florian Wegwitz, Patrick Hermann, Mark J. Truty, Jens T. Siveke, Stephan A. Hahn, Elisabeth Heßmann, Steven A. Johnsen, Zeynab Najafova   +21 more
openalex   +1 more source

Treatment landscape from first‐ to third‐line therapy and quality of life data of patients with pancreatic cancer from the prospective German PARAGON (Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer) registry (IKF‐PARAGON study)

International Journal of Cancer, EarlyView.
What's New? Pancreatic cancer often is diagnosed at advanced stages. As a result, treatment regimens frequently are aggressive, with substantial side effects that impact quality of life (QoL). This study examined the treatment landscape, from neoadjuvant therapy to palliative care, in the context of QoL among pancreatic cancer patients in Germany. Most
Thorsten O. Goetze, Salah‐Eddin Al‐Batran, Ruediger Liersch, Lars Scheuer, Thomas Goehler, Ulrich Kaiser, Claudio Denzlinger, Stephan Brandl, Daniel Pink, Jens Uhlig, Michael Maasberg, Maria Loose, Marina Schaaf, Disorn Sookthai, Bianca Zäpf, Claudia Pauligk, Timursah Habibzade, Ralf‐Dieter Hofheinz, Christine Koch, for the AIO Study Group   +19 more
wiley   +1 more source

Mitochondrial Metabolism in Pancreatic Ductal Adenocarcinoma: From Mechanism-Based Perspectives to Therapy [PDF]

, 2023
Hafiza Padinharayil, Vikrant Rai, Alex George   +2 more
openalex   +1 more source

Protein Induced by Vitamin K Absence or Antagonist‐II: Significantly Elevated in Obstructive Jaundice and Sepsis Patients Without Hepatocellular Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
The PIVKA‐II produced by HCC may differ from that produced by obstructive jaundice and sepsis. Given that serum PIVKA‐II levels are abnormally elevated in patients with obstructive jaundice and sepsis, the results should be interpreted with caution in patients with hepatocellular carcinoma combined with these diseases. ABSTRACT Background PIVKA‐II is a
Ke Zhang, Xiarui Ye, Xianran Fu
wiley   +1 more source

Early Definitive Surgery for Congenital Biliary Dilatation in Children Is Associated With Lower Morbidity: Comparison of Infant and School‐Age Children From 231 Consecutive Cases in a Multicenter Study in the Kyushu Area of Japan During the Past Decade

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Purpose There has been little discussion on the differences in characteristics and long‐term outcomes of congenital biliary dilation (CBD) by age group. Methods We conducted a regional multicenter study to investigate all pediatric cases of CBD in the Kyushu area of Japan over the past decade.
Masakazu Murakami, Koshiro Sugita, Shohei Maeda, Kina Miyoshi, Yusuke Yamane, Taichiro Kosaka, Shun Onishi, Makoto Hayashida, Toshiharu Matsuura, Kimio Asagiri, Motofumi Torikai, Yukihiro Tatekawa, Takeshi Yamanouchi, Taizo Hibi, Tatsuro Tajiri, Satoshi Ieiri   +15 more
wiley   +1 more source