Results 281 to 290 of about 217,476 (395)

Pancreatic Ductal Adenocarcinoma After Hepatitis C Infection.

JAMA Netw Open
Levinson RN, Bushman R, Tate JP, Skanderson M, Mezzacappa C, Park LS, Brandt CA, Schuster KM, Ketwaroo GA, Yang YX, Justice AC, Wang LL.   +11 more
europepmc   +1 more source

Repurposing DPP-4 inhibitors as anticancer agents in KRAS-mutated pancreatic ductal adenocarcinoma. [PDF]

BMC Pharmacol Toxicol
Ramalingam PS, Hussain MS, Chellasamy G, Elangovan S, Sharma D, T P, Mishra RAK, Kodiveri Muthukaliannan G, Hussain T, Alrokayan S, Balakrishnan P, Mekala JR, Arumugam S.   +12 more
europepmc   +1 more source

The GABAergic Shield: Loss of Tonic Metabotropic Inhibition Unmasks Oncogenic Ionotropic Signaling in Pancreatic Ductal Adenocarcinoma

CHOI, IL WOONG
openalex   +1 more source

Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma

, 2016
Pratiek N. Matkar, Krishna K. Singh, Dmitriy Rudenko, Yu Jin Kim, Michael A. Kuliszewski, Gérald J. Prud’homme, David W. Hedley, Howard Leong‐Poi   +7 more
openalex   +2 more sources

A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models

Cancer Science, EarlyView.
We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa, Daisuke Komura, Takayuki Isagawa, Yusuke Amano, Atsushi Kihara, Tamaki Miura, Taichiro Yoshimoto, Hiroyoshi Tsubochi, Kazutaka Fujita, Koichi Hagiwara, Makoto Maemondo, Tetsuo Ushiku, Shumpei Ishikawa, Noriyoshi Fukushima, Kentaro Inamura, Daisuke Matsubara, Toshiro Niki   +16 more
wiley   +1 more source

Supplementary Figure 3 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8⁺ T cells Infiltrating Pancreatic Ductal Adenocarcinoma [PDF]

Zoe C. Schmiechen, Hezkiel A. Nanda, Adam L. Burrack, Grant H. Hickok, Jonah Z. Butler, Eduardo Cruz-Hinojoza, Nicholas J. Maurice, Michael J. Geuenich, Chengxin Yu, Alexander K. Tsai, Cara-lin Lonetree, Madeline A. Ellefson, Audrey L. Hilk, Brandon M. Larsen, Ebony A. Miller, A. Rizzo, Kieran R. Campbell, Steven S. Shen, Ingunn M. Stromnes   +18 more
openalex   +1 more source

A YAP/TAZ–CDC6 Axis Initiates and Maintains Malignant Transformation

Cancer Science, EarlyView.
This study demonstrates that constitutive activation of YAP or TAZ is sufficient to induce and maintain malignant transformation in fibroblasts, identifying them as essential oncogenic drivers. Transcriptomic and functional analyses revealed CDC6 as a critical downstream effector of YAP/TAZ, with elevated expression linked to tumorigenesis across ...
David Nduru, Yudai Ohta, Akihiro Nita, Mayumi Niimura, Samson Ngurari, Toshiro Moroishi   +5 more
wiley   +1 more source

Nonredundant Immune Checkpoints Direct Therapeutic Resistance to Chemoimmunotherapy in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Immunol Res
Stone ML, Herrera VM, Li Y, Coho H, Xue Y, Graham K, Ratmansky J, Delman D, O'Brien S, Beatty GL.   +9 more
europepmc   +1 more source

Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial‐Mesenchymal Transition Pathway

Cancer Science, EarlyView.
BACH1 is associated with poor prognosis in BC patients and plays a critical role in promoting tumor progression and metastasis. Furthermore, we elucidated the mechanism by which BACH1 facilitates tumor progression and metastasis, primarily through activation of the EMT pathway. These findings suggest that BACH1 may serve as a novel prognostic biomarker
Tomoya Hatayama, Kenshiro Takemoto, Kohei Kobatake, Kento Miura, Liyanage P. Perera, Ryoken Yamanaka, Kazuma Yukihiro, Hiroyuki Shikuma, Kyosuke Iwane, Ryo Tasaka, Yuki Kohada, Miki Naito, Shunsuke Miyamoto, Yohei Sekino, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Osamu Kaminuma, Nobuyuki Hinata   +19 more
wiley   +1 more source

Diagnostic Stratification of Pancreatic Ductal Adenocarcinoma via Metallomics and Blood-Based Biomarkers. [PDF]

Diagnostics (Basel)
Coradduzza D, Perra T, Sibono L, Sanna A, Cossu M, Azara EG, Petracca F, Madeddu RB, De Miglio MR, Carru C, Grosso M, Cossu ML, Medici S.   +12 more
europepmc   +1 more source